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4-Methylquinolin-7-ol is a quinoline-based organic compound characterized by the presence of a methyl group at the 4th position and a hydroxyl group at the 7th position. It is a derivative of quinoline and has garnered interest due to its potential biological activities, such as antimicrobial and anticancer properties, as well as its utility in the synthesis of pharmaceutical compounds. This versatile compound holds promise for various applications in the fields of pharmacology and medicinal chemistry.

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  • 15463-09-9 Structure
  • Basic information

    1. Product Name: 4-Methylquinolin-7-ol
    2. Synonyms: 4-Methylquinolin-7-ol
    3. CAS NO:15463-09-9
    4. Molecular Formula: C10H9NO
    5. Molecular Weight: 159.18456
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 15463-09-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 330.0±22.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.210±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: Inert atmosphere,Room Temperature
    8. Solubility: N/A
    9. PKA: 8.93±0.40(Predicted)
    10. CAS DataBase Reference: 4-Methylquinolin-7-ol(CAS DataBase Reference)
    11. NIST Chemistry Reference: 4-Methylquinolin-7-ol(15463-09-9)
    12. EPA Substance Registry System: 4-Methylquinolin-7-ol(15463-09-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 15463-09-9(Hazardous Substances Data)

15463-09-9 Usage

Uses

Used in Pharmaceutical Synthesis:
4-Methylquinolin-7-ol is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic benefits.
Used in Antimicrobial Applications:
4-Methylquinolin-7-ol is employed as an antimicrobial agent, demonstrating effectiveness against a range of microorganisms. Its ability to disrupt microbial processes makes it a valuable component in the development of new antimicrobial drugs.
Used in Anticancer Applications:
4-Methylquinolin-7-ol is used as an anticancer agent, showing potential in inhibiting the growth and proliferation of cancer cells. Its mechanism of action may involve targeting specific cellular pathways or processes, offering a novel approach to cancer treatment.
Used in Medicinal Chemistry Research:
4-Methylquinolin-7-ol serves as a valuable research tool in medicinal chemistry, aiding scientists in understanding the structure-activity relationships of quinoline-based compounds. Its study contributes to the advancement of drug discovery and the development of more effective therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 15463-09-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,4,6 and 3 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 15463-09:
(7*1)+(6*5)+(5*4)+(4*6)+(3*3)+(2*0)+(1*9)=99
99 % 10 = 9
So 15463-09-9 is a valid CAS Registry Number.

15463-09-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-hydroxy-4-methylquinoline

1.2 Other means of identification

Product number -
Other names 7-Hydroxy-lepidin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15463-09-9 SDS

15463-09-9Downstream Products

15463-09-9Relevant articles and documents

Microwave-assisted simple synthesis of quinolines from anilines and alkyl vinyl ketones on the surface of silica gel in the presence of indium(III) chloride

Ranu, Brindaban C.,Hajra, Alakananda,Jana, Umasish

, p. 531 - 533 (2000)

A simple and efficient procedure has been developed for the synthesis of 4-alkylquinolines by a one-pot reaction of anilines with alkyl vinyl ketones on the surface of silica gel impregnated with indium(III) chloride under microwave irradiation without any solvent.

High-yielding microwave assisted synthesis of quinoline and dihydroquinoline derivatives under solvent-free conditions

Bose, D. Subhas,Kumar, Racherla Kishore

, p. 549 - 559 (2007/10/03)

A mild and efficient solvent-free method has been developed by two different approaches for the synthesis of quinoline and dihydroquinoline derivatives: (i) one-pot reaction of anilines with alkyl vinyl ketones (Skraup reaction) (ii) between various acetophenones and 2-aminoacetophenone (Friedlaender reaction) using stable and effective heterogeneous catalyst potassium dodecatangestocobaltate (25 mol %) (PDTC) under microwave irradiation in high yields.

Efficient microwave-assisted synthesis of quinolines and dihydroquinolines under solvent-free conditions

Ranu, Brindaban C.,Hajra, Alakananda,Dey, Suvendu S.,Jana, Umasish

, p. 813 - 819 (2007/10/03)

A convenient and efficient procedure for the synthesis of quinolines and dihydroquinolines has been developed by a simple one-pot reaction of anilines with alkyl vinyl ketones on the surface of silica gel impregnated with indium(III) chloride under microwave irradiation without any solvent.

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