15463-09-9

Basic information

• Product Name: 4-Methylquinolin-7-ol
• Synonyms: 4-Methylquinolin-7-ol
• CAS NO: 15463-09-9
• Molecular Formula: C10H9NO
• Molecular Weight: 159.18456
• Mol File: 15463-09-9.mol

Chemical Properties

• Boiling Point: 330.0±22.0 °C(Predicted)
• Appearance: /
• Density: 1.210±0.06 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 8.93±0.40(Predicted)
• CAS DataBase Reference: 4-Methylquinolin-7-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methylquinolin-7-ol(15463-09-9)
• EPA Substance Registry System: 4-Methylquinolin-7-ol(15463-09-9)

Safety Data

• Hazardous Substances Data: 15463-09-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
4-Methylquinolin-7-ol is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic benefits.
Used in Antimicrobial Applications:
4-Methylquinolin-7-ol is employed as an antimicrobial agent, demonstrating effectiveness against a range of microorganisms. Its ability to disrupt microbial processes makes it a valuable component in the development of new antimicrobial drugs.
Used in Anticancer Applications:
4-Methylquinolin-7-ol is used as an anticancer agent, showing potential in inhibiting the growth and proliferation of cancer cells. Its mechanism of action may involve targeting specific cellular pathways or processes, offering a novel approach to cancer treatment.
Used in Medicinal Chemistry Research:
4-Methylquinolin-7-ol serves as a valuable research tool in medicinal chemistry, aiding scientists in understanding the structure-activity relationships of quinoline-based compounds. Its study contributes to the advancement of drug discovery and the development of more effective therapeutic agents.

Upstream product

• 78-94-4 methyl vinyl ketone 
• 591-27-5 m-Hydroxyaniline 

Relevant articles and documents

Microwave-assisted simple synthesis of quinolines from anilines and alkyl vinyl ketones on the surface of silica gel in the presence of indium(III) chloride

A simple and efficient procedure has been developed for the synthesis of 4-alkylquinolines by a one-pot reaction of anilines with alkyl vinyl ketones on the surface of silica gel impregnated with indium(III) chloride under microwave irradiation without any solvent.

High-yielding microwave assisted synthesis of quinoline and dihydroquinoline derivatives under solvent-free conditions

A mild and efficient solvent-free method has been developed by two different approaches for the synthesis of quinoline and dihydroquinoline derivatives: (i) one-pot reaction of anilines with alkyl vinyl ketones (Skraup reaction) (ii) between various acetophenones and 2-aminoacetophenone (Friedlaender reaction) using stable and effective heterogeneous catalyst potassium dodecatangestocobaltate (25 mol %) (PDTC) under microwave irradiation in high yields.

Efficient microwave-assisted synthesis of quinolines and dihydroquinolines under solvent-free conditions

A convenient and efficient procedure for the synthesis of quinolines and dihydroquinolines has been developed by a simple one-pot reaction of anilines with alkyl vinyl ketones on the surface of silica gel impregnated with indium(III) chloride under microwave irradiation without any solvent.