155560-04-6 Usage
Uses
Used in Neurological Disorders Treatment:
N-(3-endo)-9-Azabicyclo[3.3.1]non-3-ylcarbamic acid 1,1-dimethylethyl ester is used as a therapeutic agent for neurological disorders, specifically targeting Parkinson's disease and other conditions characterized by dopamine dysregulation. Its ability to selectively inhibit the DAT makes it a promising candidate for improving motor symptoms and potentially slowing disease progression.
Used in Psychiatric Disorders Treatment:
In the psychiatric field, N-(3-endo)-9-Azabicyclo[3.3.1]non-3-ylcarbamic acid 1,1-dimethylethyl ester is utilized as a treatment for anxiety and depression. Its anxiolytic and antidepressant effects, as demonstrated in animal studies, suggest that it could be a valuable addition to the pharmacological arsenal for managing these conditions.
Used in Research and Development:
N-(3-endo)-9-Azabicyclo[3.3.1]non-3-ylcarbamic acid 1,1-dimethylethyl ester serves as a valuable tool in research for understanding the role of dopamine in various neurological and psychiatric conditions. Its selective inhibition of the DAT allows scientists to study the effects of dopamine dysregulation and develop new therapeutic strategies for related disorders.
Used in Drug Development:
As a selective inhibitor of the DAT, N-(3-endo)-9-Azabicyclo[3.3.1]non-3-ylcarbamic acid 1,1-dimethylethyl ester is employed in the development of new drugs aimed at treating disorders related to dopamine dysregulation. Its unique mechanism of action and potential therapeutic effects make it a promising candidate for further research and development in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 155560-04-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,5,5,6 and 0 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 155560-04:
(8*1)+(7*5)+(6*5)+(5*5)+(4*6)+(3*0)+(2*0)+(1*4)=126
126 % 10 = 6
So 155560-04-6 is a valid CAS Registry Number.
155560-04-6Relevant articles and documents
Synthesis of analogs of the radiation mitigator JP4-039 and visualization of BODIPY derivatives in mitochondria
Frantz, Marie-Céline,Skoda, Erin M.,Sacher, Joshua R.,Epperly, Michael W.,Goff, Julie P.,Greenberger, Joel S.,Wipf, Peter
, p. 4147 - 4153 (2013/07/19)
JP4-039 is a lead structure in a series of nitroxide conjugates that are capable of accumulating in mitochondria and scavenging reactive oxygen species (ROS). To explore structure-activity relationships (SAR), new analogs with variable nitroxide moieties were prepared. Furthermore, fluorophore-tagged analogs were synthesized and provided the opportunity for visualization in mitochondria. All analogs were tested for radioprotective and radiomitigative effects in 32Dcl3 cells.
2-ALKYLBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS
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Page/Page column 14, (2008/12/08)
Compounds of formulae I and II: are disclosed as 5-HT3 inhibitors. Those compounds are useful in treating CINV, IBS-D and other diseases and conditions.
