155583-45-2Relevant articles and documents
A method of preparing veratryl acetone (by machine translation)
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Paragraph 0030; 0031, (2016/10/17)
The invention discloses a method for preparing of acetone veratryl, is the by-product of the to the benzofuranol 4 - (2-methyl propyl) - 1,2-dihydroxybenzene and methane chloride as the raw material, with a strong base as acid-binding agent, in a solvent of water, and phase transfer catalyst under a high pressure condition by etherification reaction intermediates of the 1,2-dimethoxy-4 - (2-methyl-propyl) benzene. Then 1,2-dimethoxy-4 - (2-methyl-propyl) benzene in the solvent acetic acid in the oxidation reaction with ozone, then the reduction with zinc powder, products prepared veratryl acetone. Reaction formula is as follows: The invention has realized the utilization of waste material, to meet the environmental protection, the requirements of economic development cycle. The resulting intermediate 4 - (2-methyl propyl) - 1,2-dihydroxybenzene quality is high, the preparation of high-quality products to lay a good foundation for veratryl acetone. The process is simple, the operation is convenient, easy availability of raw materials, the production cost is cheap, is beneficial for the industrial production. The product yield is high, the total yield is greater than 70%, the product quality is high, quality content 98% or more. (by machine translation)
Hydroalkoxylation of unactivated olefins with carbon radicals and carbocation species as key intermediates
Shigehisa, Hiroki,Aoki, Tatsuya,Yamaguchi, Sumiko,Shimizu, Nao,Hiroya, Kou
supporting information, p. 10306 - 10309 (2013/08/23)
A unique Markovnikov hydroalkoxylation of unactivated olefins with a cobalt complex, silane, and N-fluoropyridinium salt is reported. Further optimization of reaction conditions yielded high functional group tolerance and versatility of alcoholic solvent employed, including methanol, i-propanol, and t-butanol. Use of trifluorotoluene as a solvent made the use of alcohol in stoichiometric amount possible. Mechanistic insight into this novel catalytic system is also discussed. Experimental results suggest that catalysis involves both carbon radical and carbocation intermediates.
Synthesis and radical scavenging activity of 3,3-dialkyl-3,4-dihydro-isoquinoline 2-oxides
Bernotas, Ronald C.,Thomas, Craig E.,Carr, Albert A.,Nieduzak, Thaddeus R.,Adams, Ginette,Ohlweiler, David F.,Hay, David A.
, p. 1105 - 1110 (2007/10/03)
The syntheses and antioxidant activities of several cyclic nitrones related to phenyl t-butyl nitrone (PBN) are described. These nitrones may act as radical scavengers and have potential uses in the treatment of stroke and septic shock. Copyright