156001-51-3

Basic information

• Product Name: 5-BROMO-2-METHYLBENZONITRILE
• Synonyms: 5-BROMO-2-METHYLBENZONITRILE,98%;5-Bromo-2-methylbenzonotrile;Bromo-2-methylbenzonitrile;3-BROMO-6-METHYLBENZONITRILE;5-BROMO-2-METHYLBENZONITRILE
• CAS NO: 156001-51-3
• Molecular Formula: C₈H₆BrN
• Molecular Weight: 196.04
• Product Categories: Aromatic Nitriles;C8 to C9;Cyanides/Nitriles;Nitrogen Compounds
• Mol File: 156001-51-3.mol

Chemical Properties

• Melting Point: 47-51 °C
• Boiling Point: 251℃
• Flash Point: 110 °C
• Appearance: /
• Density: 1.51
• Vapor Pressure: 0.021mmHg at 25°C
• Refractive Index: 1.591
• Storage Temp.: Room temperature.
• Solubility: soluble in Methanol
• CAS DataBase Reference: 5-BROMO-2-METHYLBENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-METHYLBENZONITRILE(156001-51-3)
• EPA Substance Registry System: 5-BROMO-2-METHYLBENZONITRILE(156001-51-3)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• RIDADR: UN 3439 6.1/PG III
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 156001-51-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
5-Bromo-2-Methylbenzonitrile is used as a reagent for the synthesis of pharmaceuticals, contributing to the development of new drugs and medications. Its chemical properties make it a valuable component in the creation of various medicinal compounds.
Used in Manufacturing Industry:
5-Bromo-2-Methylbenzonitrile is used as a building block in the manufacturing industry, playing a crucial role in the production of various industrial products. Its versatility in organic reactions allows for its incorporation into a wide range of materials and applications.
Used in Laboratory Research:
5-Bromo-2-Methylbenzonitrile is used as a reagent in laboratory settings, where it is employed in a variety of organic reactions and experiments. Its reactivity and potential hazards require that it be managed under controlled circumstances to ensure safety and proper handling.
Note: Since the provided materials do not mention specific industries or application types, the uses are generalized based on the information given. If more specific applications or industries are mentioned in the materials, they should be included in the organized description.

InChI:InChI=1/C8H6BrN/c1-6-2-3-8(9)4-7(6)5-10/h2-4H,1H3

Upstream product

• 50670-64-9 3-cyano-4-methylaniline 
• 939-83-3 2-cyano-4-nitrotoluene 
• 529-19-1 2-Methylbenzonitrile 

Downstream Products

• 79669-49-1 5-bromo-2-methylbenzoic acid 
• 523977-64-2 5-bromo-2-formylbenzonitrile 
• 523977-67-5 5-Bromo-2-[(E)-2-(4-bromo-phenyl)-vinyl]-benzonitrile 
• 523977-68-6 C₁₆H₈Br₂N₂ 
• 523977-70-0 5-Bromo-2-[(E)-2-(4-diphenylamino-phenyl)-vinyl]-benzonitrile 
• 90050-59-2 5-bromo-2-methylbenzaldehyde 
• 911210-49-6 (3-cyano-4-methylphenyl)boronic acid 
• 1254319-29-3 (S)-tert-butyl 4-(1-amino-3-(3'-cyano-4'-methylbiphenyl-4-yl)-1-oxopropan-2-ylcarbamoyl)tetrahydro-2H-pyran-4-ylcarbamate 
• 1318689-68-7 4-(5-(p-(naphthylphenylamino)phenyl)-3,4-ethylenedioxythiophen-2-yl)-2-cyanobenzaldehyde 

Relevant articles and documents

Highly efficient triarylene conjugated dyes for sensitized solar cells

A new series of organic dyes containing a triarylamine donor group, a triarylene-linked bridging moiety, and a cyanoacrylic acid acceptor group were synthesized through a simple procedure in high yields. A selected set of substituents were added onto the

Dual Pharmacophores - PDE4-Muscarinic Antagonistics

The present invention is directed to novel compounds of Formula (I) and pharmaceutically acceptable salts thereof, pharmaceutical compositions and their use as dual chromaphores having inhibitory activity against PDE4 and muscarinic acetylcholine receptors (mAChRs), and thus being useful for treating respiratory diseases.

Dual Pharmacophores - PDE4-Muscarinic Antagonistics

The present invention relates to novel compounds of Formula (I) and their use in the treatment of respiratory diseases, including anti-inflammatory and allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, rhinitis (e.g. allergic rhinitis), atopic dermatitis or psoriasis.

Dual Pharmacophores - PDE4-Muscarinic Antagonistics

The present invention is directed to novel compounds of Formula (I), pharmaceutical compositions and their use in therapy, for example as inhibitors of phosphodiesterase type IV (PDE4) and as antagonists of muscarinic acetylcholine receptors (mAChRs), in the treatment of/and or prophylaxis of respiratory diseases, including antiinflammatory and/or allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, rhinitis (e.g. allergic rhinitis), atopic dermatitis or psoriasis.

DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS

The present invention is directed to novel compounds of Formula's (I) - (VI), and pharmaceutically acceptable salts thereof, pharmaceutical compositions and their use in therapy, for example as inhibitors of phosphodiesterase type IV (PDE4) and as antagonists of muscarinic acetylcholine receptors (mAChRs), in the treatment of and/or prophylaxis of respiratory diseases, including inflammatory and/or allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, rhinitis (e.g. allergic rhinitis), atopic dermatitis or psoriasis.

SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP)

The present invention discloses and claims a series of 2,3,5-substituted pyridone derivatives as defined herein. This invention also relates to methods of making these compounds. The compounds of this invention are inhibitors of poly(adenosine 5'-diphosphate ribose) polymerase (PARP) and are therefore useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of diseases, including diseases associated with the central nervous system and cardiovascular disorders.

Difluoromethyltriazolone compounds, use of the same and intermediates for the production thereof

A triazolone compound of the formula [I]: wherein; R1 represents optionally substituted phenyl or the like, T represents m-phenylene optionally substituted by methyl or the like; and a fungicidal composition containing it as an active ingredient.

Synthesis and spectroscopic properties of finite Ph 2N-containing oligo(arylenevinylene) derivatives that emit blue to red fluorescence

(Matrix presented) A series of oligo(phenylenevinylene) (OPV) derivatives with finite conjugation units were prepared in short steps from few building blocks. The central and terminal aryl groups of these OPV dyes contain cyano and Ph2N substituents, respectively, which affect color of fluorescence. The wavelength ranges from 472 nm (blue) to 614 nm (red) depending on the position of the cyano group.

Trisubstituted biphenyls

Antihypertensive and antiatherosclerotic trisubstituted biphenyls of the formula STR1 in which R1 represents a carboxyl radical or represents a C1 -C8 -alkoxycarbonyl radical, R2 represents straight-chain or bra