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CHEMBRDG-BB 6164257 is a chemical compound with the chemical formula C23H13N3O4S2. It is an inhibitor of ATP citrate lyase, an enzyme that plays a crucial role in the production of fatty acids and cholesterol. CHEMBRDG-BB 6164257 has been studied for its potential therapeutic effects in treating metabolic diseases and cancer, as well as for its potential use as a tool compound in research on the role of ATP citrate lyase in various biological processes. Further research is needed to fully understand the properties and potential applications of CHEMBRDG-BB 6164257.

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  • 156006-08-5 Structure
  • Basic information

    1. Product Name: CHEMBRDG-BB 6164257
    2. Synonyms: CHEMBRDG-BB 6164257;7-(1-METHYL-2-OXOPROPOXY)-2H-CHROMEN-2-ONE;OTAVA-BB 7210430016;7-(1-methyl-2-oxopropoxy)-2H-chromen-2-one(SALTDATA: FREE);7-(1-methyl-2-oxopropoxy)-2-chromenone;7-(1-methyl-2-oxo-propoxy)chromen-2-one;7-(2-keto-1-methyl-propoxy)coumarin;7-(3-oxobutan-2-yloxy)chromen-2-one
    3. CAS NO:156006-08-5
    4. Molecular Formula: C13H12O4
    5. Molecular Weight: 232.23
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 156006-08-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 404.1°C at 760 mmHg
    3. Flash Point: 182.1°C
    4. Appearance: /
    5. Density: 1.234g/cm3
    6. Vapor Pressure: 9.71E-07mmHg at 25°C
    7. Refractive Index: 1.554
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: CHEMBRDG-BB 6164257(CAS DataBase Reference)
    11. NIST Chemistry Reference: CHEMBRDG-BB 6164257(156006-08-5)
    12. EPA Substance Registry System: CHEMBRDG-BB 6164257(156006-08-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 156006-08-5(Hazardous Substances Data)

156006-08-5 Usage

Uses

Used in Pharmaceutical Industry:
CHEMBRDG-BB 6164257 is used as a therapeutic agent for the treatment of metabolic diseases and cancer. Its ability to inhibit ATP citrate lyase may help regulate the production of fatty acids and cholesterol, offering potential benefits in managing these conditions.
Used in Research and Development:
CHEMBRDG-BB 6164257 is used as a tool compound in research on the role of ATP citrate lyase in various biological processes. This can help scientists better understand the enzyme's function and its potential as a target for drug development.
Further research is needed to explore the full potential of CHEMBRDG-BB 6164257 in these applications and to identify any additional uses in other industries.

Check Digit Verification of cas no

The CAS Registry Mumber 156006-08-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,0,0 and 6 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 156006-08:
(8*1)+(7*5)+(6*6)+(5*0)+(4*0)+(3*6)+(2*0)+(1*8)=105
105 % 10 = 5
So 156006-08-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H12O4/c1-8(14)9(2)16-11-5-3-10-4-6-13(15)17-12(10)7-11/h3-7,9H,1-2H3

156006-08-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-(3-oxobutan-2-yloxy)chromen-2-one

1.2 Other means of identification

Product number -
Other names 7-(1-methylacetonyloxy)coumarin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:156006-08-5 SDS

156006-08-5Downstream Products

156006-08-5Relevant articles and documents

A fluorescence-based assay for Baeyer-Villiger monooxygenases, hydroxylases and lactonases

Sicard, Renaud,Chen, Lu S.,Marsaioli, Anita J.,Reymond, Jean-Louis

, p. 1041 - 1050 (2007/10/03)

Alkylation of umbelliferone and nitrophenol with chloroacetone, 3-chlorobutanone, 2-chlorocyclopentanone and 2-chlorocyclohexanone gave the corresponding 2-coumaryloxy and 2-nitrophenoxy ketones. The 2-coumaryloxy ketones were used as fluorogenic substrates to detect Baeyer-Villiger monooxygenases activities of microbial cultures in highthroughput using microtiter plates. The 2-coumaryloxy ketones were oxidized by microorganisms producing Baeyer-Villiger monooxygenases (BVMO), releasing umbelliferone as a fluorescent signal. The substrates were also biotransformed by a microbial monooxygenase (Trichosporon cutaneum). Chemical Baeyer-Villiger oxidation of 2-coumaryloxy ketones using meta-chloroperbenzoic acid proceeded regioselectively to the corresponding acyloxyalkyl derivatives of umbelliferone and nitrophenol. These chiral lactones underwent a fluorogenic and chromogenic reaction upon hydrolysis by esterases, in particular pig liver esterase. Enantioselectivity of the ester hydrolysis reaction was determined by chiral-phase analysis of the unreacted lactones.

Synthesis and characterization of new methylpsoralens as potential photochemotherapeutic agents

Antonello,Zagotto,Mobilio,Marzano,Gia,Uriarte

, p. 277 - 280 (2007/10/02)

Three new psoralens with methyl groups on carbons involved in their reactive double bonds (compounds 9-11 in Scheme 1) were synthesized from the corresponding 7-hydroxycoumarins by cyclization of acetonyl derivatives of the latter in an alkaline medium. In preliminary tests, the new methyl-substituted psoralens exhibited considerable interaction in the dark with DNA, good photoreactivity against the macromolecule, and also interesting antiproliferative activity.

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