156137-99-4 Usage
Uses
Used in Anesthesia:
Rapacuronium is used as an adjunct to general anesthesia for surgical procedures. It is particularly useful due to its rapid onset and short duration of action, making it a suitable alternative to the depolarizing agent succinylcholine with a very short duration of action.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Rapacuronium is used as a nondepolarizing neuromuscular blocking drug. Its synthesis involves a three-step process starting from the 3-hydroxy-androstan-17-one analog and is quaternized with allyl bromide. Rapacuronium's relatively low potency (ED90 = 1.15 mg/kg) makes it a valuable compound for developing anesthesia medications.
Brand Name:
Rapacuronium bromide is marketed under the brand name Raplon.
Check Digit Verification of cas no
The CAS Registry Mumber 156137-99-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,1,3 and 7 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 156137-99:
(8*1)+(7*5)+(6*6)+(5*1)+(4*3)+(3*7)+(2*9)+(1*9)=144
144 % 10 = 4
So 156137-99-4 is a valid CAS Registry Number.
InChI:InChI=1/C37H61N2O4.BrH/c1-6-20-39(21-12-9-13-22-39)32-24-30-28-15-14-27-23-33(42-26(3)40)31(38-18-10-8-11-19-38)25-37(27,5)29(28)16-17-36(30,4)35(32)43-34(41)7-2;/h6,27-33,35H,1,7-25H2,2-5H3;1H/q+1;/p-1/t27-,28+,29-,30-,31-,32-,33-,35-,36-,37-;/m0./s1
156137-99-4Relevant articles and documents
Monoquaternary 2,16-bispiperidinylandrostane derivatives
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, (2008/06/13)
Monoquaternary 2,16-bispiperidinylandrostane neuromuscular blocking derivatives having the formula: STR1 wherein R1 is ethyl; R2 is methyl or allyl; and X- is a pharmaceutically acceptable anion; or pharmaceutically acceptable salts thereof.
Novel 2β,16β-diamino-androstanes
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, (2008/06/13)
2β,16β-diamino-3α,17α-oxygenated androstanes having one quaternized group, process for the preparation of these compounds and pharmaceutical compositions comprising such compounds as the active ingredient. The aforementioned compounds are favourable neuro