156212-81-6 Usage
Bicyclic structure
Benzimidazole derivative
The compound has a bicyclic structure, which means it consists of two fused rings, with one being a benzene ring and the other being an imidazole ring.
Presence of chlorine atom
6-chloro
The compound contains a chlorine atom at the 6th position of the benzimidazole ring, which can influence its reactivity and properties.
Presence of methyl group
1-methyl
A methyl group (CH3) is attached to the 1st position of the benzimidazole ring, which can affect the compound's steric and electronic properties.
Heterocyclic compound
Contains two nitrogen atoms
The compound is classified as a heterocyclic compound due to the presence of two nitrogen atoms in its bicyclic structure.
Potential applications
Research and industrial applications
The compound may be used as a building block for the synthesis of pharmaceuticals, agrochemicals, and other organic compounds.
Biological activities
Possible medicinal properties
The compound may have potential biological activities and medicinal properties, making it a subject of interest for further studies.
Chemical and physical properties
Influenced by chlorine and methyl groups
The presence of a chlorine atom and a methyl group in the compound gives it specific chemical and physical properties, which can be exploited in various applications.
CAS Registry Number
9CI
The compound is registered under the Chemical Abstracts Service (CAS) Registry with the identification number 9CI.
Check Digit Verification of cas no
The CAS Registry Mumber 156212-81-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,2,1 and 2 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 156212-81:
(8*1)+(7*5)+(6*6)+(5*2)+(4*1)+(3*2)+(2*8)+(1*1)=116
116 % 10 = 6
So 156212-81-6 is a valid CAS Registry Number.
156212-81-6Relevant articles and documents
Synthesis and antiprotozoal activity of novel 1-methylbenzimidazole derivatives
Valdez-Padilla, David,Rodriguez-Morales, Sergio,Hernandez-Campos, Alicia,Hernandez-Luis, Francisco,Yepez-Mulia, Lilian,Tapia-Contreras, Amparo,Castillo, Rafael
experimental part, p. 1724 - 1730 (2009/08/08)
In this paper are reported the synthesis and antiprotozoal activity in vitro of 24 1-methylbenzimidazole derivatives (13-36) substituted at position 2 with aminocarbonyl, N-methylaminocarbonyl, N,N-dimethylaminocarbonyl, ethoxycarbonyl, 1-hydroxyethyl and acetyl groups, some of them with chlorine atoms at the benzenoid ring. Compounds 13-36 were more active than metronidazole, the choice drug against Giardia intestinalis and most of them against Trichomonas vaginalis. The most active group of compounds for both parasites was that with a 2-ethoxycarbonyl group (16, 22, 28, 34), independently of the substitution pattern at the benzenoid ring.
Design and synthesis of 3-(benzimidazol-2-yl)-propionic acids as thromboxane A2 receptor antagonists
Garuti,Ghedini,Leoni,Baraldi,Dionisotti
, p. 1531 - 1546 (2007/10/02)
A series of 3-(benzimidazol-2-yl)-propionic acids substituted at the N1 nitrogen with methyl and benzyl groups and at the C5 and C6 positions with chloro, methoxy, amino, hydroxyl groups were synthesized and tested as TXA2 receptor antagonists.
