156333-95-8Relevant articles and documents
High-yielding synthesis of 1-isoindolinone derivatives via palladium-catalysed cycloaminocarbonylation
Marosv?lgyi-Haskó, Diána,Takács, Attila,Riedl, Zsuzsanna,Kollár, László
experimental part, p. 1036 - 1040 (2011/03/19)
1-Isoindolinone derivatives were synthesised in high yields (up to 89%) by using 2-iodobenzyl bromide and 2-iodobenzylamine as bifunctional substrates in palladium-catalysed carbonylation. Depending on the N-nucleophiles, two types of compounds were synth
An approach to α-substituted amines
Williams, Lorenzo,Booth, Susan E.,Undheim, Kjell
, p. 13697 - 13708 (2007/10/02)
A number of amines have been alkylated at the position alpha to nitrogen via free radical methodology. N-(2-iodobenzyl) and N-(2-iodobenzoyl) 'protected' amines have been used to generate radicals which rapidly undergo a 1,5-hydrogen shift to give more st
α-Alkylation of Amines via a 1,5-Hydrogen Shift
Undheim, Kjell,Williams, Lorenzo
, p. 883 - 884 (2007/10/02)
Radicals derived from N-(2-iodobenzyl) 'protected' amines undergo a 1,5-hydrogen shift to give more stable α-amino radicals, which can be subsequently trapped by electron deficient alkenes.
