156336-70-8

Basic information

• Product Name: 4-[5-(4-CHLOROPHENYL)-1H-PYRAZOL-3-YL]PIPERIDINE
• Synonyms: 4-[5-(4-CHLOROPHENYL)-1H-PYRAZOL-3-YL]PIPERIDINE
• CAS NO: 156336-70-8
• Molecular Formula: C₁₄H₁₆ClN₃
• Molecular Weight: 261.75
• Mol File: 156336-70-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-[5-(4-CHLOROPHENYL)-1H-PYRAZOL-3-YL]PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[5-(4-CHLOROPHENYL)-1H-PYRAZOL-3-YL]PIPERIDINE(156336-70-8)
• EPA Substance Registry System: 4-[5-(4-CHLOROPHENYL)-1H-PYRAZOL-3-YL]PIPERIDINE(156336-70-8)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• Hazardous Substances Data: 156336-70-8(Hazardous Substances Data)

Upstream product

• 1042768-01-3 tert-butyl 4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidine-1-carboxylate 
• 1349863-93-9 tert-butyl 4-[3-(4-chlorophenyl)prop-2-ynoyl]piperidine-1-carboxylate 
• 139290-70-3 tert-butyl 4-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate 
• 84358-13-4 N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 156337-47-2 3-[1-(4-chlorobenzyl)piperidin-4-yl]-5-(4-chlorophenyl)pyrazole 
• 156336-93-5 4-[3-(4-chlorophenyl)-1H-pyrazol-5-yl]-1-(2-phenylethyl)piperidine. 
• 1349861-81-9 2-{3-(4-chlorophenyl)-5-[1-(2-phenylethyl)piperidin-4-yl]-1H-pyrazol-1-yl}pyrimidine. 
• 1349861-82-0 2-{5-(4-chlorophenyl)-3-[1-(2-phenylethyl)piperidin-4-yl]-1H-pyrazol-1-yl}pyrimidine. 
• 1349862-22-1 4-[1-benzyl-5-(4-chlorophenyl)-1H-pyrazol-3-yl]-1-(2-phenylethyl)piperidine 
• 1349862-25-4 4-[1-benzyl-3-(4-chlorophenyl)-1H-pyrazol-5-yl]-1-(2-phenylethyl)piperidine 
• 156336-83-3 3-(1-benzylpiperidin-4-yl)-5-(4-chlorophenyl)pyrazole 

Relevant articles and documents

Synthesis and Pharmacological Evaluation of Novel Pyrazolyl Piperidine Derivatives as Effective Antiplatelet Agents

The synthesis and antiplatelet activity of substituted pyrazolyl piperidine derivatives (3a–n) are described. These compounds were synthesized by an improved ring opening reaction of 2-arylidene quinuclidinone using hydrazine hydrate under mild conditions

NOVEL PROLYLCARBOXYPEPTIDASE INHIBITORS

Compounds of structural formula I are inhibitors of prolylcarboxypeptidase (PrCP). The compounds of the present invention are useful for the prevention and treatment of conditions related to the enzymatic activity of PrCP such as abnormal metabolism, incl

DOPAMINE RECEPTOR SUBTYPE LIGANDS

Compounds of formula (I) STR1 wherein one of X and Y represents nitrogen, and the other of X and Y represents oxygen, sulphur or N--R 2 ; Q represents a substituted five-or six-membered monocyclic heteroaliphatic ring which contains one nitrogen atom as t

4-Heterocyclylpiperidines as selective high-affinity ligands at the human dopamine D4 receptor

5-(4-Chlorophenyl)-3-(1-(4-chlorobenzyl)piperidin-4-yl)pyrazole (3) was identified from screening of the Merck sample collection as a human dopamine D4 (hD4) receptor ligand with moderate affinity (61 nM) and 4-fold selectivity over human D2 (hD2) recepto