Diastereoselective conjugate addition to chiral α,β-unsaturated carbonyl systems in aqueous media: An enantioselective entry to α- and γ-hydroxy acids and α-amino acids
The stereoselectivity of the ultrasonically induced zinc-copper conjugate addition of iodides to chiral α,βunsaturated carbonyl systems under aqueous conditions was studied. Alkyl iodides add diastereoselectively to methylenedioxolanone 1 and methyleneoxa
Suarez, Rosa M.,Perez Sestelo, Jose,Sarandeses, Luis A.
Synthesis of some 2-C-alkyl-2,3-dideoxy-α,β-L-glycero-tetrurono-1,4-lactones. Evaluation as antitumor agents
A series of 3-C-alkyl-2,3-dideoxy-5-O-trityl-D-erythro-pentono-1,4-lactones were detritylated.The resultant free-hydroxy compounds were converted to their respective 2-C-alkyl-2,3-dideoxy-α,β-L-glycero-tetrurono-1,4-lactones (L-sugar numbering) in a one-v
Blazis, Vincent J.,Hawkins, Elma S.,Baker, David C.