Efficient syntheses of polyamine and polyamine amide voltage-sensitive calcium channel blockers: FTX-3.3 and sFTX-3.3
Efficient syntheses of FTX-3.3 and sFTX-3.3, voltage-sensitive calcium channel blockers are described. These modified polyamines were prepared from selectively protected polyamines and purified on a practical scale.
Rapid, Practical Syntheses of the Arginyl Polyamine sFTX-3.3: a Blocker of Voltage-Sensitive Calcium Channels
sFTX-3.3, a polyamine toxin analogue, has been synthesized from tri-CBZ-L-arginine.Rapid, practical procedures to prepare this calcium channel blocker are presented.
Moya, Eduardo,Blagbrough, S. Ian
p. 2061 - 2062
(2007/10/02)
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