Welcome to LookChem.com Sign In|Join Free

CAS

  • or

157496-83-8

[(2R,3S,4R,5R)-5-[6-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl]-2H-purin-9-yl]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl (hydroxy-phosphonooxy-phosphoryl) hydrogen phosphate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

157496-83-8 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

  • [(2R,3S,4R,5R)-5-[6-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl]-2H-purin-9-yl]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl (hydroxy-phosphonooxy-phosphoryl) hydrogen phosphate

    Cas No: 157496-83-8

  • Need to discuss

  • No requirement

  • Adequate

  • LEAP CHEM Co., Ltd.
  • Contact Supplier

  • [(2R,3S,4R,5R)-5-[6-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl]-2H-purin-9-yl]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl (hydroxy-phosphonooxy-phosphoryl) hydrogen phosphate

    Cas No: 157496-83-8

  • Need to discuss

  • No requirement

  • Adequate

  • Hunan Wistar Imp. & Exp. Co., Ltd.
  • Contact Supplier
  • 157496-83-8 Structure

  • Basic information

    1. Product Name: [(2R,3S,4R,5R)-5-[6-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl]-2H-purin-9-yl]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl (hydroxy-phosphonooxy-phosphoryl) hydrogen phosphate
    2. Synonyms:
    3. CAS NO:157496-83-8
    4. Molecular Formula: C15H27N5O20P4
    5. Molecular Weight: 721.2914
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 157496-83-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 1046.8°C at 760 mmHg
    3. Flash Point: 586.9°C
    4. Appearance: N/A
    5. Density: 2.67g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.897
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: [(2R,3S,4R,5R)-5-[6-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl]-2H-purin-9-yl]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl (hydroxy-phosphonooxy-phosphoryl) hydrogen phosphate(CAS DataBase Reference)
    11. NIST Chemistry Reference: [(2R,3S,4R,5R)-5-[6-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl]-2H-purin-9-yl]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl (hydroxy-phosphonooxy-phosphoryl) hydrogen phosphate(157496-83-8)
    12. EPA Substance Registry System: [(2R,3S,4R,5R)-5-[6-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl]-2H-purin-9-yl]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl (hydroxy-phosphonooxy-phosphoryl) hydrogen phosphate(157496-83-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 157496-83-8(Hazardous Substances Data)

157496-83-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 157496-83-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,7,4,9 and 6 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 157496-83:
(8*1)+(7*5)+(6*7)+(5*4)+(4*9)+(3*6)+(2*8)+(1*3)=178
178 % 10 = 8
So 157496-83-8 is a valid CAS Registry Number.

157496-83-8Relevant articles and documents

Campylobacter jejuni adenosine triphosphate phosphoribosyltransferase is an active hexamer that is allosterically controlled by the twisting of a regulatory tail

Mittelst?dt, Gerd,Moggré, Gert-Jan,Panjikar, Santosh,Nazmi, Ali Reza,Parker, Emily J.

, p. 1492 - 1506 (2016)

Adenosine triphosphate phosphoribosyltransferase (ATP-PRT) catalyzes the first committed step of the histidine biosynthesis in plants and microorganisms. Here, we present the functional and structural characterization of the ATP-PRT from the pathogenic ε-proteobacteria Campylobacter jejuni (CjeATP-PRT). This enzyme is a member of the long form (HisGL) ATP-PRT and is allosterically inhibited by histidine, which binds to a remote regulatory domain, and competitively inhibited by AMP. In the crystalline form, CjeATP-PRT was found to adopt two distinctly different hexameric conformations, with an open homohexameric structure observed in the presence of substrate ATP, and a more compact closed form present when inhibitor histidine is bound. CjeATP-PRT was observed to adopt only a hexameric quaternary structure in solution, contradicting previous hypotheses favoring an allosteric mechanism driven by an oligomer equilibrium. Instead, this study supports the conclusion that the ATP-PRT long form hexamer is the active species; the tightening of this structure in response to remote histidine binding results in an inhibited enzyme.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 157496-83-8