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CAS

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157977-99-6

3-oxido-7-oxo-3-(phenoxycarbonyl)-2,4,6-trioxa-3lambda~5~-phosphaoct-1-yl acetate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 157977-99-6 Structure

  • Basic information

    1. Product Name: 3-oxido-7-oxo-3-(phenoxycarbonyl)-2,4,6-trioxa-3lambda~5~-phosphaoct-1-yl acetate
    2. Synonyms: Phosphinecarboxylic acid, bis((acetyloxy)methoxy)-, phenyl ester, oxide; Phosphinecarboxylic acid, bis[(acetyloxy)methoxy]-, phenyl ester, oxide
    3. CAS NO:157977-99-6
    4. Molecular Formula: C13H15O9P
    5. Molecular Weight: 346.2266
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 157977-99-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 421.5°C at 760 mmHg
    3. Flash Point: 222.1°C
    4. Appearance: N/A
    5. Density: 1.366g/cm3
    6. Vapor Pressure: 2.6E-07mmHg at 25°C
    7. Refractive Index: 1.501
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 3-oxido-7-oxo-3-(phenoxycarbonyl)-2,4,6-trioxa-3lambda~5~-phosphaoct-1-yl acetate(CAS DataBase Reference)
    11. NIST Chemistry Reference: 3-oxido-7-oxo-3-(phenoxycarbonyl)-2,4,6-trioxa-3lambda~5~-phosphaoct-1-yl acetate(157977-99-6)
    12. EPA Substance Registry System: 3-oxido-7-oxo-3-(phenoxycarbonyl)-2,4,6-trioxa-3lambda~5~-phosphaoct-1-yl acetate(157977-99-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 157977-99-6(Hazardous Substances Data)

157977-99-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 157977-99-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,7,9,7 and 7 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 157977-99:
(8*1)+(7*5)+(6*7)+(5*9)+(4*7)+(3*7)+(2*9)+(1*9)=206
206 % 10 = 6
So 157977-99-6 is a valid CAS Registry Number.

157977-99-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name [acetyloxymethoxy(phenoxycarbonyl)phosphoryl]oxymethyl acetate

1.2 Other means of identification

Product number -
Other names Bis(Acetyloxymethyl) phenyl foscarnet

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:157977-99-6 SDS

157977-99-6Downstream Products

157977-99-6Relevant articles and documents

Synthesis, hydrolytic behavior, and anti-HIV activity of selected acyloxyalkyl esters of trisodium phosphonoformate (foscarnet sodium)

Iyer,Boal,Phillips,Thakker,Egan

, p. 1269 - 1273 (2007/10/02)

The synthesis and anti-HIV activity of selected (acyloxy)-alkyl esters of trisodium phosphonoformate (foscarnet sodium) are described. The conversion of bis(trimethylsilyl) (alkoxycarbonyl)phosphonates 11a-d to the corresponding disilver salts 12a-d and their subsequent reaction with iodoalkyl acrylates 4a-c gave the desired bis(acyloxyalkyl) phosphonates 6- 9(a-c). Of the analogs tested, only the dichlorophenyl analog 9a showed a dose-dependent inhibition of HIV activity in H9 cells. Using 31P-NMR, bioreversibility has been investigated in an attempt to rationalize these results.

Synthesis of acyloxyalkyl acylphosphonates as potential prodrugs of the antiviral, trisodium phosphonoformate (foscarnet sodium)

Iyer,Phillips,Biddle,Thakker,Egan

, p. 7141 - 7144 (2007/10/02)

Bis(trimethylsilyl) acylphosphonates via their silver salts couple with iodoalkyl esters to provided an efficient synthesis of the corresponding acyloxyalkyl esters as potential prodrugs of the antiviral agent, trisodium phophonoformate. These compounds were tested as inhibitors of HIV-1 in chronically infected H9 cells.

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