158727-56-1

Basic information

• Product Name: 2-METHOXY-4-(TRIFLUOROMETHYL)ANILINE
• Synonyms: 2-METHOXY-4-(TRIFLUOROMETHYL)ANILINE;2-Methoxy-4-(trifluoromethyl)aniline, 2-Amino-5-(trifluoromethyl)anisole
• CAS NO: 158727-56-1
• Molecular Formula: C₈H₈F₃NO
• Molecular Weight: 191.1504296
• Mol File: 158727-56-1.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 2-METHOXY-4-(TRIFLUOROMETHYL)ANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXY-4-(TRIFLUOROMETHYL)ANILINE(158727-56-1)
• EPA Substance Registry System: 2-METHOXY-4-(TRIFLUOROMETHYL)ANILINE(158727-56-1)

Safety Data

• Hazardous Substances Data: 158727-56-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Methoxy-4-(trifluoromethyl)aniline is used as an intermediate in the synthesis of various pharmaceuticals for its ability to enhance the biological activity of compounds, contributing to the development of new medications.
Used in Agrochemical Industry:
In agrochemicals, 2-Methoxy-4-(trifluoromethyl)aniline serves as an intermediate, playing a crucial role in the creation of effective crop protection agents and other agricultural products.
Used in Organic Compounds Synthesis:
2-Methoxy-4-(trifluoromethyl)aniline is used as a building block in the preparation of various organic compounds, leveraging its chemical properties to form a wide range of products.
Used in Dyes and Pigments Industry:
2-METHOXY-4-(TRIFLUOROMETHYL)ANILINE is utilized as a building block for the preparation of dyes and pigments, where its unique structure contributes to the color and properties of the final products.
Used in Polymers Industry:
2-Methoxy-4-(trifluoromethyl)aniline is used in the synthesis of polymers, where its structural features can influence the polymer's characteristics, such as stability and reactivity.
Used as a Reagent in Organic Synthesis:
In organic synthesis, 2-Methoxy-4-(trifluoromethyl)aniline functions as a reagent, facilitating various chemical reactions and contributing to the formation of desired products.
Used as a UV Absorber:
2-Methoxy-4-(trifluoromethyl)aniline is employed as a UV absorber in certain applications, protecting materials from the damaging effects of ultraviolet radiation.

Upstream product

• 402-12-0 2-fluoro-1-nitro-4-(trifluoromethyl)benzene 
• 914636-97-8 2-methoxy-1-nitro-4-(trifluoromethyl)benzene 
• 98-17-9 3-Trifluoromethylphenol 
• 887144-94-7 Togni's reagent II 
• 90-04-0 2-methoxy-phenylamine 

Downstream Products

• 900863-31-2 1-(2-methoxy-4-trifluoromethylphenyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea 

Relevant articles and documents

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Nickel-Catalyzed Direct C-H Trifluoromethylation of Free Anilines with Togni's Reagent

An efficient nickel-catalyzed C-H trifluoromethylation for the synthesis of trifluoromethylated free anilines using Togni's reagent has been developed. This approach exhibits a good functional group tolerance, good regioselectivity, and chemoselectivity under mild conditions. The newly developed economical one-step method is a better alternative to synthesize trifluoromethylated free anilines.