159414-97-8 Usage
Uses
Used in Oncology:
N4-Acetyl-2'-Fluoro-2'-deoxycytidine is used as an antineoplastic agent for its potential in treating various types of cancer. It is particularly effective against solid tumors and hematologic malignancies due to its ability to inhibit DNA synthesis and repair, thereby disrupting tumor cell growth.
Used in Cancer Research:
In the field of cancer research, N4-Acetyl-2'-Fluoro-2'-deoxycytidine is utilized for its potential to replace cytidine in RNA during transcription and interfere with enzymes involved in DNA replication. This makes it a valuable tool for studying the mechanisms of tumor growth and identifying new therapeutic targets.
Used in Drug Development:
N4-Acetyl-2'-Fluoro-2'-deoxycytidine is being investigated for its potential use in the development of new cancer treatments. Its unique properties as a nucleoside analog and its ability to inhibit DNA synthesis and repair make it a promising candidate for further research and development in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 159414-97-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,9,4,1 and 4 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 159414-97:
(8*1)+(7*5)+(6*9)+(5*4)+(4*1)+(3*4)+(2*9)+(1*7)=158
158 % 10 = 8
So 159414-97-8 is a valid CAS Registry Number.
159414-97-8Relevant articles and documents
NOVEL CHROMOPHORIC SILYL PROTECTING GROUPS AND THEIR USE IN THE CHEMICAL SYNTHESIS OF OLIGONUCLEOTIDES
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Page/Page column 30; 41, (2009/01/20)
The present invention provides compounds of the formula (I): C-Q-O-Si (R1)(R2)-N wherein C is a chromophore; Q is selected from the group consisting of optionally substituted aliphatic, aryl, heteroaryl, cycloalkyl or heterocycloalkyl; R1 and R2 are independently selected from the group consisting of optionally substituted C1-8 alkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, C1-8 alkyloxy, cycloalkyloxy, heterocycloalkyloxy, alkylsilyloxy and arylsilyloxy; and N is a glycosylamine or abasic moiety.
Oligoribonucleotide and ribozyme analogs with terminal 3′—3′ and/or 5′—5′ linkages
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, (2008/06/13)
The invention relates to oligoribonucleotide analogs with terminal 3′—3′ and/or 5′—5′ internucleotide linkages. This modification stabilizes the molecules altered in this way, including ribozymes, without adversely altering their properties, including, where appropriate, catalytic activities.
