159503-24-9

Basic information

• Product Name: 4'-AMINO-BIPHENYL-3-CARBOXYLIC ACID METHYL ESTER
• Synonyms: SALOR-INT L480207-1EA;SALOR-INT L480592-1EA;AKOS BAR-0134;AKOS BAR-0153;3'-AMINOBIPHENYL-4-CARBOXYLIC ACID METHYL ESTER;4'-AMINO-BIPHENYL-3-CARBOXYLIC ACID METHYL ESTER;METHYL 3'-AMINO[1,1'-BIPHENYL]-4-CARBOXYLATE;METHYL 4'-AMINO[1,1'-BIPHENYL]-3-CARBOXYLATE
• CAS NO: 159503-24-9
• Molecular Formula: C₁₄H₁₃NO₂
• Molecular Weight: 227.26
• Mol File: 159503-24-9.mol

Chemical Properties

• Boiling Point: 411.779 °C at 760 mmHg
• Flash Point: 242.097 °C
• Appearance: /
• Density: 1.166 g/cm³
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 4.05±0.10(Predicted)
• CAS DataBase Reference: 4'-AMINO-BIPHENYL-3-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-AMINO-BIPHENYL-3-CARBOXYLIC ACID METHYL ESTER(159503-24-9)
• EPA Substance Registry System: 4'-AMINO-BIPHENYL-3-CARBOXYLIC ACID METHYL ESTER(159503-24-9)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 159503-24-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4'-Amino-biphenyl-3-carboxylic acid methyl ester is used as a key intermediate in the synthesis of various drugs and medicine formulations, contributing to the development of novel therapeutic agents.
Used in Scientific Research:
As a research chemical, 4'-Amino-biphenyl-3-carboxylic acid methyl ester is utilized in scientific studies and experiments, aiding in the exploration of new chemical reactions and the advancement of organic chemistry.

Upstream product

• 591-19-5 m-Bromoaniline 
• 89900-93-6 3'-nitro-[1,1'-biphenyl]-4-carboxylic acid methyl ester 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 13331-27-6 m-nitrobenzene boronic acid 
• 5798-75-4 Ethyl 4-bromobenzoate 

Relevant articles and documents

Synthesis and biological evaluation of a novel photo-activated histone deacetylase inhibitor

Hydroxamic acid-based histone deacetylase inhibitors (HDACi) are a class of epigenetic agents with potentially broad therapeutic application to several disease states including post angioplasty mediated neointimal hyperplasia (NIH). Precise spatiotemporal

HEPATITIS B CORE PROTEIN ALLOSTERIC MODULATORS

ABSTRACT The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.

Biarylaniline phenethanolamines as potent and selective β3 adrenergic receptor agonists

The synthesis of a series of phenethanolamine aniline agonists that contain an aniline ring on the right-hand side of the molecule substituted at the meta position with a benzoic acid or a pyridyl carboxylate is described. Several of the analogues (e.g.,

1, 3, 4-BENZOTRIAZEPIN-2-ONE SALTS AND THEIR USE AS CCK RECEPTOR LIGANDS

This invention relates to pharmaceutically acceptable salts of compounds of formula (I) wherein: W is N or N+-O-; R2 is an optionally substituted C1 to C18 hydrocarbyl group wherein up to three C atoms may optionally be replaced by N, O and/or S atoms. R3 is -(CR11R12)m-X-(CR13R14)p-R9; m is 0, 1, 2, 3 or 4; p is 0, 1 or 2; X is a bond, -CR15=CR16-, -C≡C-, C(O)NH, NHC(O), C(O)NMe, NMeC(O), C(O)O, NHC(O)NH, NHC(O)O, OC(O)NH, NH, O, CO, SO2, SO2NH, C(O)NHNH, R9 is H ; C1 to C6 alkyl ; or phenyl, naphthyl, pyridyl, benzimidazolyl, indazolyl, quinolinyl, isoquinolinyl, tetrahydroisoquinolinyl, indolinyl, isoindolinyl, indolyl, isoindolyl or 2-pyridonyl substituted with -L-Q. R4 is an optionally substituted C1 to C18 hydrocarbyl group wherein up to three C atoms may optionally be replaced by N, O and/or S atoms ; and Such salts are useful, for example, for the treatment of gastrin related disorders.

Palladium-catalyzed coupling of functionalized bromoarenes to a polystyrene-bound aryl tributylstannane

The Stille reaction with a polystyrene-bound stannyl component, catalyzed by a palladacycle complex, provides a convenient and clean method for the synthesis of substituted biaryls on the resin. Several functional groups useful for the construction of supported polydentate amino alcohols were successfully introduced.

Thiazolopyrimidine derivatives

Thiazolopyrimidine derivatives represented by the formula STR1 and salts thereof are provided, which are characterized by a carboxamide residue substituted with R4 and R5. The derivatives and salts thereof exhibit antiangiogenic acti