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3-amino-1-(4-fluorophenyl)-1H-benzo[f]chromene-2-carbonitrile is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 159685-77-5 Structure
  • Basic information

    1. Product Name: 3-amino-1-(4-fluorophenyl)-1H-benzo[f]chromene-2-carbonitrile
    2. Synonyms: 3-amino-1-(4-fluorophenyl)-1H-benzo[f]chromene-2-carbonitrile
    3. CAS NO:159685-77-5
    4. Molecular Formula: C20H13FN2O
    5. Molecular Weight: 316.3284232
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 159685-77-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-amino-1-(4-fluorophenyl)-1H-benzo[f]chromene-2-carbonitrile(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-amino-1-(4-fluorophenyl)-1H-benzo[f]chromene-2-carbonitrile(159685-77-5)
    11. EPA Substance Registry System: 3-amino-1-(4-fluorophenyl)-1H-benzo[f]chromene-2-carbonitrile(159685-77-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 159685-77-5(Hazardous Substances Data)

159685-77-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 159685-77-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,9,6,8 and 5 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 159685-77:
(8*1)+(7*5)+(6*9)+(5*6)+(4*8)+(3*5)+(2*7)+(1*7)=195
195 % 10 = 5
So 159685-77-5 is a valid CAS Registry Number.

159685-77-5Downstream Products

159685-77-5Relevant articles and documents

Ultrasonic-assisted preparation of Co3O4 and Eu-doped Co3O4 nanocatalysts and their application for solvent-free synthesis of 2-amino-4H-benzochromenes under microwave irradiation

Kafi-Ahmadi, Leila,Poursattar Marjani, Ahmad,Nozad, Ehsan

, (2021/05/10)

Co3O4 and Eu-doped Co3O4 nanocatalysts were synthesized through an ultrasonic-assisted solvothermal method and were characterized with X-ray diffraction (XRD), Fourier transform infrared (FT-IR), energy-dispersi

Biocompatible Ionic Liquid Promote One-Pot Synthesis of 2-Amino-4H-Chromenes Under Ambient Conditions

Zhu, Anlian,Li, Qixing,Feng, Wanlu,Fan, Dongshuang,Li, Lingjun

, p. 720 - 733 (2020/08/07)

Abstract: The synthesis of 2-amino-4H-chromenes through one-pot multicomponent reactions has received great attention due to the high atom efficiency and the broad bioactivities of the products. Here, the catalytic performances of a series of functional ionic liquids towards this type of reaction were investigated and the results showed that the ionic liquid, choline acetate ([Choline][Ac]), could efficiently promote this reactions under room temperature without the necessary of organic solvents. The reaction is easy to be conducted and the following work-up procedures are very simple. The pure products can be obtained through extraction and washing procedures, no column separation procedures are needed. Intriguingly, this reaction system can be easily scaled up to multi-gram, suggesting its perspective in industrial applications. In addition, the ionic liquid [Choline][Ac] can be easily prepared from cheap and biocompatible materials, and it can be feasibly recycled and reutilized for at least five cycles. Graphic Abstract: Various aldehydes, malononitrile and activated phenols could be converted to thecorresponding 2-amino-4H-chromenes with good to excellent isolated yields underthe catalysis of choline acetate at room temperature. [Figure not available: see fulltext.]

Synthesis of 2-amino-3-cyano-4H-pyran derivatives using GO-Fc@Fe3O4 nanohybrid as a novel recyclable heterogeneous nanocatalyst and preparation of tacrine-naphthopyran hybrids as AChE inhibitors

Mozaffarnia, Sakineh,Teimuri-Mofrad, Reza,Rashidi, Mohammad-Reza

, p. 1455 - 1470 (2021/01/05)

Abstract: GO-Fc@Fe3O4 nanohybrid as a powerful and reusable nanocatalyst was synthesized. The graphene oxide (GO) sheets with meta-chloroperoxybenzoic acid (mCPBA) were treatment, afterward were chemically modified with 4-Fc derivati

MCM-41@Schiff base-Co(OAc)2 as an efficient catalyst for the synthesis of pyran derivatives

Pan, Shiwei,Li, Puhui,Xu, Guihua,Guo, Jingchang,Ke, Libin,Xie, Canquan,Zhang, Zhoucai,Hui, Yonghai

, p. 1353 - 1371 (2019/11/20)

Heterogeneous ordered mesoporous silica materials catalyst, MCM-41@Schiff base-Co(AcO)2, reveals high catalytic performance within the synthesis of pyran derivatives using the multicomponent reaction of aldehydes, malononitrile and 2-naphthol (

Synthesis and characterization of a novel Fe3O4@SiO2-BenzIm-Fc[Cl]/BiOCl nano-composite and its efficient catalytic activity in the ultrasound-assisted synthesis of diverse chromene analogs

Mohammadi, Reza,Esmati, Somayeh,Gholamhosseini-Nazari, Mahdi,Teimuri-Mofrad, Reza

supporting information, p. 135 - 145 (2019/01/04)

In this study, a novel magnetically recoverable Fe3O4@SiO2-BenzIm-Fc[Cl]/BiOCl nano-composite was synthesized using a simple chemical co-precipitation method. This is the first time that a magnetic nano-catalyst bearing ionic liquid, ferrocene and BiOCl is synthesized. The Fe3O4@SiO2-BenzIm-Fc[Cl]/BiOCl nano-composite was characterized by Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), energy-dispersive X-ray spectroscopy (EDX) and field emission scanning electron microscopy (FE-SEM) techniques. The catalytic activities of the novel magnetic nano-composite were evaluated in one-pot three-component synthesis of a wide variety of 2-amino-3-cyano-4H-chromene derivatives under ultrasound irradiation. A simple, facile and highly efficient ultrasound-assisted method was developed to synthesize 4H-chromene derivatives via one-pot, three-component reaction of aldehyde, malononitrile and active phenolic compounds (2-naphthol, 1-naphthol, 3-(dimethylamino)phenol, resorcinol and orcinol) at room temperature. The reaction of aldehyde, malononitrile and orcinol is newly introduced in this paper. The ultrasound-assisted synthesis protocol that was studied in this article exhibits some notable advantages such as short reaction times, operational simplicity, green reaction conditions, high yields and easy work-up and purification steps. In addition, the novel magnetic nano-composite could be easily recovered by an external magnetic field and reused for six-reaction cycles without significant loss of its catalytic activity.

An Eco-friendly Catalytic System for One-pot Multicomponent Synthesis of Diverse and Densely Functionalized Pyranopyrazole and Benzochromene Derivatives

Patil,Patil, Rupesh C.,Patil, Suresh S.

, (2019/06/24)

An external base-free, efficient, cost-effective, and environmentally benign protocol has been developed for the one-pot multicomponent synthesis of highly functionalized pyranopyrazoles and benzochromenes using water extract of Agave americana (century p

Synthesis, characterization, anti-proliferative properties and DNA binding of benzochromene derivatives: Increased Bax/Bcl-2 ratio and caspase-dependent apoptosis in colorectal cancer cell line

Ahagh, Mina Hanifeh,Dehghan, Gholamreza,Mehdipour, Maryam,Teimuri-Mofrad, Reza,Payami, Elmira,Sheibani, Nader,Ghaffari, Maryam,Asadi, Milad

, (2019/10/05)

3-Amino-1-aryl-1H-benzo[f]chromene-2-carbonitrile derivatives were synthesized from three-component reaction of arylaldehyde, malononitrile and 2-naphthol in the presence of 1, 4-bis(4-ferrocenylbutyl)piperazine as a new catalyst. Cytotoxic potencies of t

Ferrocene-tagged ionic liquid stabilized on silica-coated magnetic nanoparticles: Efficient catalyst for the synthesis of 2-amino-3-cyano-4H-pyran derivatives under solvent-free conditions

Teimuri-Mofrad, Reza,Gholamhosseini-Nazari, Mahdi,Payami, Elmira,Esmati, Somayeh

, (2017/09/06)

An advanced novel magnetic ionic liquid based on imidazolium tagged with ferrocene, a supported ionic liquid, is introduced as a recyclable heterogeneous catalyst. Catalytic activity of the novel nanocatalyst was investigated in one-pot three-component re

An affordable DABCO-based ionic liquid efficiency in the synthesis of 3-amino-1-aryl-1H-benzo[f] chromene-2-carbonitrile, 1-(benzothiazolylamino)phenylmethyl-2-naphthol, and 1-(benzoimidazolylamino)phenylmethyl-2-naphthol derivatives

Nabinia, Nazanin,Shirini, Farhad,Tajik, Hassan,Mashhadinezhad, Maryam,Langarudi, Mohaddeseh Safarpoor Nikoo

, p. 2147 - 2157 (2018/08/03)

In this study, [H2-DABCO][HSO4]2 is applied as an acidic ionic liquid to exclude some disadvantages of former methods reported for the synthesis of 3-amino-1-aryl-1H-benzo[f]chromene-2-carbonitrile, 1-(benzothiazolylamino)

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