15973-07-6Relevant articles and documents
Quinone-cyclized porfiromycins
Na, Younghwa,Kohn, Harold
, p. 1347 - 1363 (2007/10/03)
Mitomycin C and porfiromycin cyclization has been implicated in the pathway for KW-2149 and BMS-181174 function. The importance of the porfiromycin C(7) structure and nucleophile for quinone cyclization was determined showing that both C(7) and C(8) annul
On the Remarkable Stability of Derivatives of Leucomitomycin F. Novel Mitomycin Analogues
Egbertson, Melissa,Danishefsky, Samuel J.,Schulte, Gayle
, p. 4424 - 4426 (2007/10/02)
The leuco form of mitomycin F reacts with silica gel in the presence of oxygen to afford 9-epimitomycin B.A notable stability is manifested by hydroquinoid forms (leucomitomycin) bearing a 9,10-exocyclic methylene group.