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CAS

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160730-42-7

(8beta,10xi)-8-{[2-(4-methoxyphenyl)-1H-imidazol-1-yl]methyl}-6-methylergoline is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • (8beta,10xi)-8-{[2-(4-methoxyphenyl)-1H-imidazol-1-yl]methyl}-6-methylergoline

    Cas No: 160730-42-7

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  • 160730-42-7 Structure

  • Basic information

    1. Product Name: (8beta,10xi)-8-{[2-(4-methoxyphenyl)-1H-imidazol-1-yl]methyl}-6-methylergoline
    2. Synonyms:
    3. CAS NO:160730-42-7
    4. Molecular Formula: C26H28N4O
    5. Molecular Weight: 412.5267
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 160730-42-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 645.8°C at 760 mmHg
    3. Flash Point: 344.4°C
    4. Appearance: N/A
    5. Density: 1.3g/cm3
    6. Vapor Pressure: 1.45E-16mmHg at 25°C
    7. Refractive Index: 1.701
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: (8beta,10xi)-8-{[2-(4-methoxyphenyl)-1H-imidazol-1-yl]methyl}-6-methylergoline(CAS DataBase Reference)
    11. NIST Chemistry Reference: (8beta,10xi)-8-{[2-(4-methoxyphenyl)-1H-imidazol-1-yl]methyl}-6-methylergoline(160730-42-7)
    12. EPA Substance Registry System: (8beta,10xi)-8-{[2-(4-methoxyphenyl)-1H-imidazol-1-yl]methyl}-6-methylergoline(160730-42-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 160730-42-7(Hazardous Substances Data)

160730-42-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 160730-42-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,0,7,3 and 0 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 160730-42:
(8*1)+(7*6)+(6*0)+(5*7)+(4*3)+(3*0)+(2*4)+(1*2)=107
107 % 10 = 7
So 160730-42-7 is a valid CAS Registry Number.

160730-42-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (6aR,9R)-9-[[2-(4-methoxyphenyl)imidazol-1-yl]methyl]-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:160730-42-7 SDS

160730-42-7Downstream Products

160730-42-7Relevant articles and documents

Synthesis and structure-activity relationships of new (5R,8R,10R)-ergoline derivatives with antihypertensive or dopaminergic activity

Ohno,Adachi,Koumori,Mizukoshi,Nagasaka,Ichihara,Kato -

, p. 1463 - 1473 (2007/10/02)

A series of new (5R,8R,10R)-ergoline derivatives was synthesized, and their antihypertensive and dopaminergic activities were tested in conscious spontaneously hypertensive rats and in rats with unilateral 6- hydroxydopamine-induced lesions of the substantia nigra. (5R,8R,10R)-6- Alkyl-8-ergolinemethanols, prepared from the corresponding ergolinecarboxylates, were converted to the tosylates, which were treated with various five-membered heterocycles containing nitrogen atoms to afford the new ergolines. (5R,8R,10R)-8-(1,2,4-Triazol-1-ylmethyl)-6-methylergoline (4s, maleate: BAM-1110) exhibited potent dopaminergic activity, about 18- fold greater than that of bromocriptine mesylate. (5R,8R,10R)-8-(1,2,4- Triazol-1-ylmethyl)-6-propylergoline (8b, fumarate: BAM-1602) showed extremely potent dopaminergic activity, being about 220 and 1.15 times more active than bromocriptine mesylate and pergolide mesylate, respectively. Several compounds exhibited potent antihypertensive activity. Structure- activity relationships for antihypertensive and dopaminergic activities are discussed.

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