161185-37-1Relevant articles and documents
A convenient one-pot synthesis of pyrano[3,2-c]quinolin-2,5(6H)-dione and 2H,5H-pyrano[3,2-c]chromene-2,5-dione derivatives
Sheibani, Hassan,Mosslemin, Mohammad Hossein,Behzadi, Soheila,Islami, Mohammad Reza,Saidi, Kazem
, p. 435 - 438 (2007/10/03)
The preparation of novel pyrano[3,2-c]quinolin-2,5(6H)-dione and 2H,5H-pyrano[3,2-c]chromene-2,5-dione derivatives starting from 4-hydroxyquinolin-2(1H)-ones and 4-hydroxy-2H-chromene-2-one with chlorocarbonyl ketenes is described. This method provides a new route to produce fused pyrano derivatives in good to excellent yields in a short experimental time. Georg Thieme Verlag Stuttgart.
Syntheses of 3-Acyl-4-hydroxy-2(1H)-quinolones
Kappe, Thomas,Aigner, Rudolf,Hohengassner, Peter,Stadlbauer, Wolfgang
, p. 596 - 601 (2007/10/02)
3-Acyl-4-hydroxy-2(1H)-quinolones 5 are obtained by hydrolytic ring opening and subsequent decarboxylation from the corresponding pyranoquinolin-2,5(6H)-diones 4, which in turn are easily obtained from 1:2 condensation of of anilines 1 with diethyl malonate 2a or 1:1 condensation of diethyl alkyl- or arylmalonates 2b-e with 4-hydroxy-2(1H)-quinolones 3.Nitropyranoquinolinediones 6 furnish after ringopening 3-nitroacetyl-4-hydroxy-2(1H)-quinolones 8.Pyranoquinolines 7 and 9 with acetyl- or aminosubstituents are hydrolyzed during basic ringopening to yield 5.