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16124-22-4

UDP-N-acetylmuramic acid pentapeptide is a complex molecule that plays a crucial role in the synthesis of bacterial cell walls. It is composed of UDP-N-acetylmuramic acid (UDP-MurNAc), a derivative of muramic acid, which is a key component of peptidoglycan, the structural polymer that provides strength and shape to bacterial cell walls. The pentapeptide chain, which consists of five amino acids (usually L-alanine, D-glutamic acid, L-lysine, D-alanine, and D-alanine), is attached to the UDP-MurNAc. This combination forms the basic building block for the elongation of the peptidoglycan chain, which is essential for bacterial cell growth and division. The synthesis and assembly of this molecule are critical for bacterial survival, making it a potential target for the development of new antibiotics.

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  • 16124-22-4 Structure

  • Basic information

    1. Product Name: UDP-N-acetylmuramic acid pentapeptide
    2. Synonyms: UDP-N-acetylmuramic acid pentapeptide
    3. CAS NO:16124-22-4
    4. Molecular Formula: C41H65N9O28P2
    5. Molecular Weight: 1193.945822
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 16124-22-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: °Cat760mmHg
    3. Flash Point: °C
    4. Appearance: /
    5. Density: 1.66g/cm3
    6. Refractive Index: 1.635
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 1.10±0.50(Predicted)
    10. CAS DataBase Reference: UDP-N-acetylmuramic acid pentapeptide(CAS DataBase Reference)
    11. NIST Chemistry Reference: UDP-N-acetylmuramic acid pentapeptide(16124-22-4)
    12. EPA Substance Registry System: UDP-N-acetylmuramic acid pentapeptide(16124-22-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 16124-22-4(Hazardous Substances Data)

16124-22-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 16124-22-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,1,2 and 4 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 16124-22:
(7*1)+(6*6)+(5*1)+(4*2)+(3*4)+(2*2)+(1*2)=74
74 % 10 = 4
So 16124-22-4 is a valid CAS Registry Number.
InChI:InChI=1/C41H65N9O28P2/c1-14(32(58)46-15(2)35(60)61)45-33(59)20(8-6-18(25(43)37(64)65)21(52)9-7-19(42)36(62)63)47-39(67)41(5,49-17(4)51)31(57)16(3)75-30-26(44)38(66)77-23(28(30)55)13-74-80(71,72)78-79(69,70)73-12-22-27(54)29(56)34(76-22)50-11-10-24(53)48-40(50)68/h10-11,14-16,18-20,22-23,25-30,34,38,54-56,66H,6-9,12-13,42-44H2,1-5H3,(H,45,59)(H,46,58)(H,47,67)(H,49,51)(H,60,61)(H,62,63)(H,64,65)(H,69,70)(H,71,72)(H,48,53,68)/t14-,15-,16?,18?,19+,20+,22-,23-,25?,26-,27-,28-,29-,30-,34?,38+,41-/m1/s1

16124-22-4Downstream Products

16124-22-4Relevant articles and documents

Purification and biochemical characterization of Mur ligases from Staphylococcus aureus

Patin, Delphine,Boniface, Audrey,Kova?, Andreja,Hervé, Mireille,Dementin, Sébastien,Barreteau, Hélne,Mengin-Lecreulx, Dominique,Blanot, Didier

, p. 1793 - 1800 (2010)

The Mur ligases (MurC, MurD, MurE and MurF) catalyze the stepwise synthesis of the UDP-N-acetylmuramoyl-pentapeptide precursor of peptidoglycan. The murC, murD, murE and murF genes from Staphylococcus aureus, a major pathogen, were cloned and the correspo

Preparative Enzymatic Synthesis and Characterization of the Cytoplasmic Intermediates of Murein Biosynthesis

Reddy, Sreelatha G.,Waddell, Sherman T.,Kuo, David W.,Wong, Kenny K.,Pompliano, David L.

, p. 1175 - 1178 (1999)

The first six cytoplasmic intermediates of murein biosynthesis (2-7) have been prepared in high yield (>60%) and at preparative scale (10-100 mg) using purified enzymes of the murein biosynthetic pathway (MurA-MurF). For at least three of these compounds,

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