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16200-53-6

3-NORADAMANTANECARBOXYLIC ACID is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 16200-53-6 Structure

  • Basic information

    1. Product Name: 3-NORADAMANTANECARBOXYLIC ACID
    2. Synonyms: 3-NORADAMANTANCARBOXYLIC ACID;3-NORADAMANTANECARBOXYLIC ACID;3-NORADAMANTANECARBOXYLIC ACID 97%;3-Carboxynoradamantane;3-Noradmantanecarboxylic acid.;Hexahydro-2,5-methanopentalene-3a(1H)-carboxylic acid;Tricyclo[3.3.1.03,7]nonane-3-carboxylic acid;3-Noradamantanecarboxylic acid,98%
    3. CAS NO:16200-53-6
    4. Molecular Formula: C10H14O2
    5. Molecular Weight: 166.22
    6. EINECS: N/A
    7. Product Categories: Adamantane derivatives;Stains&Dyes, A to;N;Stains and Dyes
    8. Mol File: 16200-53-6.mol

  • Chemical Properties

    1. Melting Point: 104-108 °C
    2. Boiling Point: 234.44°C (rough estimate)
    3. Flash Point: 133.1°C
    4. Appearance: White/Crystalline Powder and Chunks or Crystals
    5. Density: 0.9817 (rough estimate)
    6. Vapor Pressure: 0.001mmHg at 25°C
    7. Refractive Index: 1.4859 (estimate)
    8. Storage Temp.: N/A
    9. Solubility: almost transparency in Methanol
    10. PKA: 4.78±0.20(Predicted)
    11. Water Solubility: Insoluble
    12. CAS DataBase Reference: 3-NORADAMANTANECARBOXYLIC ACID(CAS DataBase Reference)
    13. NIST Chemistry Reference: 3-NORADAMANTANECARBOXYLIC ACID(16200-53-6)
    14. EPA Substance Registry System: 3-NORADAMANTANECARBOXYLIC ACID(16200-53-6)

  • Safety Data

    1. Hazard Codes: Xi,C,F
    2. Statements: 36/37/38-34-11
    3. Safety Statements: 37/39-26-45-36/37/39-16-37
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 16200-53-6(Hazardous Substances Data)

16200-53-6 Usage

Chemical Properties

white crystalline powder and chunks or crystals

Check Digit Verification of cas no

The CAS Registry Mumber 16200-53-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,2,0 and 0 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 16200-53:
(7*1)+(6*6)+(5*2)+(4*0)+(3*0)+(2*5)+(1*3)=66
66 % 10 = 6
So 16200-53-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H14O2/c11-9(12)10-4-6-1-7(5-10)3-8(10)2-6/h6-8H,1-5H2,(H,11,12)/p-1/t6-,7+,8?,10?

16200-53-6 Well-known Company Product Price

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  • Alfa Aesar

  • (A16683)  3-Noradamantanecarboxylic acid, 98%   

  • 16200-53-6

  • 0.25g

  • 328.0CNY

  • Detail

  • Alfa Aesar

  • (A16683)  3-Noradamantanecarboxylic acid, 98%   

  • 16200-53-6

  • 1g

  • 962.0CNY

  • Detail

  • Alfa Aesar

  • (A16683)  3-Noradamantanecarboxylic acid, 98%   

  • 16200-53-6

  • 5g

  • 4414.0CNY

  • Detail

16200-53-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-NORADAMANTANECARBOXYLIC ACID

1.2 Other means of identification

Product number -
Other names 3-Carboxynoradamantane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16200-53-6 SDS

16200-53-6Relevant articles and documents

Discovery of adamantane based highly potent HDAC inhibitors

Gopalan, Balasubramanian,Ponpandian, Thanasekaran,Kachhadia, Virendra,Bharathimohan, Kuppusamy,Vignesh, Radhakrishnan,Sivasudar, Velaiah,Narayanan, Shridhar,Mandar, Bhonde,Praveen, Rajendran,Saranya, Nithyanandan,Rajagopal, Sriram,Rajagopal, Sridharan

, p. 2532 - 2537 (2013/06/27)

Herein, we report the development of highly potent HDAC inhibitors for the treatment of cancer. A series of adamantane and nor-adamantane based HDAC inhibitors were designed, synthesized and screened for the inhibitory activity of HDAC. A number of compounds exhibited GI50 of 10-100 nM in human HCT116, NCI-H460 and U251 cancer cells, in vitro. Compound 32 displays efficacy in human tumour animal xenograft model.

HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS

-

, (2011/06/16)

Described are bridged compounds of the formula (I), their analogs, tautomeric forms, stereoisomers, geometrical isomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites and prodrugs thereof. The invention relates to compositions and methods to treat fungal infection. These compounds are selective HDAC inhibitors that act as inherent antifungal compounds or enhance the activity of other antifungal compounds such as azoles.

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