162107-50-8

Basic information

• Product Name: 3-Butynoicacid,2-[[(1,1-dimethylethoxy)carbonyl]amino]-,(R)-(9CI)
• Synonyms: 3-Butynoicacid,2-[[(1,1-dimethylethoxy)carbonyl]amino]-,(R)-(9CI)
• CAS NO: 162107-50-8
• Molecular Formula: C9H13NO4
• Molecular Weight: 199.2
• Product Categories: N-BOC
• Mol File: 162107-50-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Butynoicacid,2-[[(1,1-dimethylethoxy)carbonyl]amino]-,(R)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Butynoicacid,2-[[(1,1-dimethylethoxy)carbonyl]amino]-,(R)-(9CI)(162107-50-8)
• EPA Substance Registry System: 3-Butynoicacid,2-[[(1,1-dimethylethoxy)carbonyl]amino]-,(R)-(9CI)(162107-50-8)

Safety Data

• Hazardous Substances Data: 162107-50-8(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 162107-49-5 (R)-tert-butyl (1-hydroxybut-3-yn-2-yl)carbamate 

Downstream Products

• 45121-22-0 Boc-D-Abu 
• 120157-99-5 N-propanoyl-1,1-dimethylethyl carbamate 

Relevant articles and documents

Synthesis of optically active β,γ-alkynylglycine derivatives

Full results on the first synthesis of optically active β,γ-alkynylglycine derivatives from naturally occurring L-serine are described. The methodology uses L-serinal as a key intermediate and allows great versatility in the introduction of N-protective groups and of alkyne substitution. The N-Boc protected β,γ-alkynylglycine derivatives described have ee greater than 90%.

En route to optically active ethynylglycine derivatives

First results in the synthesis of chiral non racemic ethynylglycine derivatives from protected L-serinal are described.