Rhodium(III)-catalyzed, C-H activated annulation to form isocoumarins and α-pyrones using the O-N bond as an internal oxidant
A mild, efficient and regioselective C-H activation-based intermolecular redox-neutral annulation of O-benzoylhydroxylamines and internal alkynes has been achieved. The protocol employs an O-N bond as the internal oxidant and leads to isocoumarins and α-pyrones.