162698-41-1

Basic information

• Product Name: METHANESULFONIC ACID (1-BENZHYDRYLAZETIDIN-3-YL)METHYL ESTER
• Synonyms: METHANESULFONIC ACID (1-BENZHYDRYLAZETIDIN-3-YL)METHYL ESTER;(1-benzhydrylazetidin-3-yl)methyl methanesulfonate;1-(Diphenylmethyl)-3-azetidinemethanol 3-methanesulfonate;1-Benzhydryl-3-(Mesyloxylmethyl)azetidine
• CAS NO: 162698-41-1
• Molecular Formula: C₁₈H₂₁NO₃S
• Molecular Weight: 331.43
• Mol File: 162698-41-1.mol

Chemical Properties

• Boiling Point: 470.4±25.0 °C(Predicted)
• Appearance: /
• Density: 1.231
• Storage Temp.: 2-8°C
• PKA: 6.75±0.10(Predicted)
• CAS DataBase Reference: METHANESULFONIC ACID (1-BENZHYDRYLAZETIDIN-3-YL)METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: METHANESULFONIC ACID (1-BENZHYDRYLAZETIDIN-3-YL)METHYL ESTER(162698-41-1)
• EPA Substance Registry System: METHANESULFONIC ACID (1-BENZHYDRYLAZETIDIN-3-YL)METHYL ESTER(162698-41-1)

Safety Data

• Hazardous Substances Data: 162698-41-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
METHANESULFONIC ACID (1-BENZHYDRYLAZETIDIN-3-YL)METHYL ESTER is used as an intermediate in the synthesis of various bioactive molecules for the development of pharmaceuticals. Its unique structure and reactivity contribute to the creation of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, METHANESULFONIC ACID (1-BENZHYDRYLAZETIDIN-3-YL)METHYL ESTER is employed as an intermediate in the synthesis of compounds with pesticidal or herbicidal properties, contributing to the development of effective crop protection agents.
Used as a Stabilizing Agent:
METHANESULFONIC ACID (1-BENZHYDRYLAZETIDIN-3-YL)METHYL ESTER is used as a stabilizing agent in pharmaceutical formulations to enhance the shelf life and maintain the quality of the final product. Its stabilizing properties also extend to some food products, ensuring their stability and safety for consumption.
Used in Organic Synthesis:
As a reagent in organic synthesis, METHANESULFONIC ACID (1-BENZHYDRYLAZETIDIN-3-YL)METHYL ESTER is utilized in various chemical reactions to form a wide range of organic compounds. Its versatility and reactivity make it a valuable component in the synthesis of complex organic molecules.

Upstream product

• 72351-36-1 1-diphenylmethyl-3-hydroxymethylazetidine 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 1146960-48-6 3-[(2-tert-butyl-4-fluorophenoxy)methyl]-1-(diphenylmethyl)azetidine 
• 142253-57-4 3-methanesulfonyloxymethyl-azetidine-1-carboxylic acid tert-butyl ester 
• 676125-72-7 1-(1-benzhydryl-azetidin-3-ylmethyl)-6-fluoro-1H-indole 

Relevant articles and documents

3-(4,5-substituted pyrimidinamine) phenyl derivatives and application thereof

The invention discloses 3-(4,5-substituted pyrimidinamine) phenyl derivatives and application thereof. The 3-(4,5-substituted pyrimidinamine) phenyl derivatives are compounds having a structure as shown in a formula (I) or pharmacologically acceptable sal

Optimization of a Series of Bivalent Triazolopyridazine Based Bromodomain and Extraterminal Inhibitors: The Discovery of (3R)-4-[2-[4-[1-(3-Methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-4-piperidyl]phenoxy]ethyl]-1,3-dimethyl-piperazin-2-one (AZD5153)

Here we report the discovery and optimization of a series of bivalent bromodomain and extraterminal inhibitors. Starting with the observation of BRD4 activity of compounds from a previous program, the compounds were optimized for BRD4 potency and physical

HETEROCYCLIC COMPOUND

The present invention relates to wherein each symbol is as defined in the specification. The compound of the present invention has a superior RBP4-lowering action, and is useful as a medicament for the prophylaxis or treatment of disease and condition mediated by increased RBP4.

Novel 5-HT2A receptor ligands

Compounds of formula I: are antagonists of the human 5-HT2A receptor, and hence useful in treatment or prevention of a variety of neurological conditions.