163704-71-0

The invention provides a preparation method of a diafenthiuron impurity C. According to the preparation method of the diafenthiuron impurity C, 2, 6-isopropylaniline, 4-toluenesulfonyl chloride, phenol, N, N-diisopropylethylamine and the like are used as

A series of aluminum complexes bearing amidate ligands, including acylamide, sulfonamide, and aryl carbamate, was synthesized. In addition, the optimization of ring-opening polymerization of ε-caprolactone by using these aluminum complexes as catalysts was studied. Polymerization results revealed that steric bulky groups in anilinyl groups decreased the catalytic activity of aluminum sulfonamide complexes but increased that of aluminum-acylamide complexes. Compared with other complexes bearing N-(4-methoxyphenyl) acylamidate and N-(4-methoxyphenyl) p-tolylsulfonamidate, an aluminum complex (MfOMeAlMe2) bearing methyl (4-methoxyphenyl)carbamate had the highest catalytic activity with an ideal molecular weight control and narrow polydispersity index (PDI). Other poly-ε-caprolactones with special end chains, such as PEG-200, 2-dimethylaminoethanol, bis(2-hydroxyethyl) disulfide, 2-((2-hydroxyethyl)disulfanyl)ethyl 2-bromo-2-methylpropanoate, and PEG-polyester-bearing disulfide group, were successfully synthesized using MfOMeAlMe2 as the catalyst. The polymerization of δ-valerolactone and 2-bromo-ε-caprolactone by using BnOH as an initiator and MfOMeAlMe2 as the catalyst resulted in poly-δ-valerolactone and poly-2-bromo-ε-caprolactone, respectively, with a precise molecular weight and a narrow PDI as well as poly-ε-caprolactones.

The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.

Chemical double mutant cycles have been used to measure the magnitude of edge-to-face aromatic interactions in hydrogen-bonded zipper complexes as a function of substituents on both aromatic rings. The interaction energies vary depending on the combinatio