164165-77-9Relevant articles and documents
Improved synthetic procedures for 4,7,2′,7′-tetrachloro- and 4′,5′-dichloro-2′,7′-dimethoxy-5(and 6)-carboxyfluoresceins
Lyttle, Matthew H.,Carter, Tim G.,Cook, Ronald M.
, p. 45 - 49 (2001)
Literature syntheses of 4,7,2′,7′-tetrachloro-5(and 6)-carboxyfluorescein ("5 and 6 TET") 1 and 4′,5′-dichloro-2′,7′-dimethoxy-5(and 6)-carboxyfluorescein ("5 and 6 JOE") 2 are reviewed, and new, preparatively useful methods are presented. A three-step synthesis of 1 was developed, which proved to be more efficient than the published seven step synthesis of this compound. The published synthesis of 2 also proved difficult to reproduce, and a better workup of the key intermediate 2-chloro-4-methoxy resorcinol was devised. Isolation of purified single isomers of both dyes is described.
Electrophoretic tag reagents comprising fluorescent compounds
-
, (2008/06/13)
Electrophoretic probes comprising fluorescent compounds as detection groups and mobility modifiers are disclosed for the multiplexed detection of the binding of, or interaction between, one or more ligands and target antiligands are provided. In one embod
Compositions and methods employing cleavable electrophoretic tag reagents
-
, (2008/06/13)
Probe sets for the multiplexed detection of the binding of, or interaction between, one or more ligands and target antiligands are provided. Detection involves the release of identifying tags as a consequence of target recognition. The probe sets include
Electrophoretic tag reagents comprising fluorescent compounds
-
, (2008/06/13)
Electrophoretic probes comprising fluorescent compounds as detection groups and mobility modifiers are disclosed for the multiplexed detection of the binding of, or interaction between, one or more ligands and target antiligands are provided. In one embod
