164171-56-6

Basic information

• Product Name: 2-(5-ISOXAZOLYL)-4-METHYLPHENOL
• Synonyms: 2-(5-ISOXAZOLYL)-4-METHYLPHENOL;2-(ISOXAZOL-5-YL)-4-METHYLPHENOL;5-(2'-HYDROXY-5'-METHYLPHENYL)-ISOXAZOLE;5-(2-Hydroxy-5-methylphenyl)isoxazole (2-(5-Isoxazolyl)-4-methylphenol);2-(5-Isoxazolyl)-4-methylphenol 98%
• CAS NO: 164171-56-6
• Molecular Formula: C₁₀H₉NO₂
• Molecular Weight: 175.18
• Product Categories: Isoxazoles, Oxadiazoles, Oxazoles;Building Blocks;Heterocyclic Building Blocks;Isoxazoles
• Mol File: 164171-56-6.mol

Chemical Properties

• Melting Point: 175-177°C
• Appearance: /
• Refractive Index: 1.573
• CAS DataBase Reference: 2-(5-ISOXAZOLYL)-4-METHYLPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-ISOXAZOLYL)-4-METHYLPHENOL(164171-56-6)
• EPA Substance Registry System: 2-(5-ISOXAZOLYL)-4-METHYLPHENOL(164171-56-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 164171-56-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-(5-Isoxazolyl)-4-methylphenol is used as a pharmaceutical intermediate for the synthesis of various drugs and therapeutic agents. Its unique structure allows it to serve as a building block for the development of novel compounds with potential medicinal properties.
Used in Agrochemical Industry:
In the agrochemical industry, 2-(5-Isoxazolyl)-4-methylphenol is utilized as an intermediate in the production of pesticides and other crop protection agents. Its chemical properties enable it to be incorporated into formulations that target specific pests or diseases, enhancing crop yield and quality.
Used in Chemical Research:
2-(5-Isoxazolyl)-4-methylphenol is also used as a research compound in various scientific studies. Its unique structure and properties make it an interesting subject for investigations into new chemical reactions, synthesis methods, and potential applications in various fields.
Used in Material Science:
In the field of material science, 2-(5-Isoxazolyl)-4-methylphenol can be employed as a component in the development of new materials with specific properties. Its incorporation into polymers, for example, may lead to the creation of materials with enhanced thermal stability, mechanical strength, or other desirable characteristics.
Overall, 2-(5-Isoxazolyl)-4-methylphenol is a versatile isoxazole derivative with a wide range of potential applications across various industries, including pharmaceuticals, agrochemicals, chemical research, and material science. Its unique structure and properties make it a valuable compound for the development of new products and technologies.

InChI:InChI=1/C10H9NO2/c1-7-2-3-9(12)8(6-7)10-4-5-11-13-10/h2-6,12H,1H3

Upstream product

• 5751-51-9 7-methyl-4H-benzopyran-4-one 
• 6921-64-8 4'-hydroxy-2'-methylacetophenone 

Downstream Products

• 99184-72-2 3-(2-hydroxy-4-methylphenyl)-3-oxopropanenitrile 

Relevant articles and documents

Synthesis of 2,2′-diaminobischromones using a modified procedure for the rearrangement of 5-(2-hydroxyphenyl)isoxazole to 2-aminochromone

A modified procedure for the rearrangement of 5-(2-hydroxyphenyl)isoxazoles 6a-e to 2-aminochromones 8a-e was developed and this procedure was utilised in the synthesis of hitherto unreported bischromones 3a-c. The isoxazoles 6a-e were prepared regioselec

Benzo-γ-pyrones. Part XV. Conversion of some 4-Oxo-4H-1-benzopyran-2-carboxylic Acids into 4H-1-Benzopyran-4-ones via Isoxazoles

The preparation of 5-substituted-3-isoxazolecarboxylic acids 2a-c and their transformation into the corresponding 2-aminochromones (5a-c) and 3-cyano-2-methylchromones (6a-c) is described. The structures of oximes of methylchromones were revised to isoxazoles 2d-f. The structures of the obtained compounds were proved by spectral methods (1H, 13C NMR, IR and MS). Key words: chromones, isoxazoles, NMR and MS spectra