165047-24-5

Basic information

• Product Name: 2,4,5-Trifluorobenzaldehyde
• Synonyms: 2,4,5-Trifluorobenzaldehyde 97%;2,4,5-Trifluorobenzaldehyde97%;2,4,5-trifluorobenzadehyde;Benzaldehyde,2,4,5-trifluoro-;2,4,5-Trifluorobenzaldehyde, 97% 1GR;2,4,5-TRIFLUOROBENZALDEHYDE;2,4,5-Trilfuorobenzaldehyde;Benzaldehyde, 2,4,5-trifluoro- (9CI)
• CAS NO: 165047-24-5
• Molecular Formula: C₇H₃F₃O
• Molecular Weight: 160.09
• EINECS: -0
• Product Categories: ALDEHYDE;HALIDE;Aromatic Aldehydes & Derivatives (substituted);Benzaldehyde;Miscellaneous;Aldehydes;C7;Carbonyl Compounds;Fluorine series
• Mol File: 165047-24-5.mol

Chemical Properties

• Boiling Point: 168 °C(lit.)
• Flash Point: 137 °F
• Appearance: Clear colorless to light yellow/Liquid
• Density: 1.408 g/mL at 25 °C(lit.)
• Vapor Pressure: 1.03E-11mmHg at 25°C
• Refractive Index: n20/D 1.482(lit.)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Water Solubility: Not miscible or difficult to mix in water.
• Sensitive: Air Sensitive
• BRN: 8479631
• CAS DataBase Reference: 2,4,5-Trifluorobenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,5-Trifluorobenzaldehyde(165047-24-5)
• EPA Substance Registry System: 2,4,5-Trifluorobenzaldehyde(165047-24-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• RIDADR: UN 1993 3/PG 1
• WGK Germany: 3
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 165047-24-5(Hazardous Substances Data)

Usage

Chemical Properties

Clear colorless to light yellow liquid

Uses

Different sources of media describe the Uses of 165047-24-5 differently. You can refer to the following data:
1. It is a reactant in the enantioselective synthesis of (R)-selegiline, an anti-Parkinson's drug, (S)-benzphetamine, an anti-obesity agent, and (S)-sitagliptin, an anti-diabetic drug.
2. 2,4,5-Trifluorobenzaldehyde may be used in the synthesis of:bis(2,4,5-trifluorophenyl)methanone8-phenyl-7-tosyl-1-(2,4,5-trifluorophenyl)octahydro-1H-pyrano[3,4-c] pyridine(E)-4-methoxy-N′-(2,4,5-trifluorobenzylidene)-benzohydrazide monohydrate

InChI:InChI=1/C5H2ClFN4/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H,8,9,10,11)

Upstream product

• 165047-23-4 2-chloro-4,5-difluorobenzaldehyde 
• 86522-91-0 2,4-dichloro-5-fluorobenzaldehyde 
• 2751-90-8 tetraphenylphosphonium bromide 

Downstream Products

• 637744-47-9 (m-tolyl)(2,4,5-trifluorobenzyl)amine 
• 888321-36-6 ethyl 3-(2,4,5-trifluorophenyl)acrylate 
• 882856-63-5 (E)-ethyl-3-(2, 4, 5-trifluorophenyl)acetate 
• 1286756-56-6 (R)-4-nitro-3-(2,4,5-trifluorophenyl)butanal 
• 1286756-57-7 (4R,5R)-tert-butyl-5-nitro-4-(2,4,5-trifluorophenyl)cyclohex-1-enecarboxylate 
• 1286756-58-8 (4R,5S)-tert-butyl-5-nitro-4-(2,4,5-trifluorophenyl)cyclohex-1-enecarboxylate 
• 1286756-59-9 (1R,2S)-2',4',5'-trifluoro-2-nitro-1,2,3,6-tetrahydro-[1,1'-biphenyl]-4-carboxylic acid 
• 1286756-60-2 ((4R,5S)-5-nitro-4-(2, 4, 5-trifluorophenyl)cyclohex-1-enyl)(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4, 3-a]pyrazin-7(8H)-yl)methanone 
• 913623-70-8 C₂HF₃O₂*C₁₉H₁₇F₆N₅O 
• 1269259-73-5 (2E,4E,6E,8E)-3,7-dimethyl-9-(2,4,5-trifluorophenyl)nona-2,4,6,8-tetraenoic acid 
• 1269260-23-2 ethyl (2E,4E,6E,8E)-3,7-dimethyl-9-(2 4 5-trifluorophenyl)nona-2 4 6 8-tetraenoate 
• 1269260-21-0 triphenyl(2,4,5-trifluorobenzyl)phosphonium bromide 
• 144284-25-3 (2,4,5-trifluorophenyl)methanol 
• 1301206-48-3 C₁₂H₁₁F₃O₂ 

Relevant articles and documents

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Process for preparing 4,5-difluorobenzaldehydes

4,5-Difluorobenzaldehydes of a given formula are prepared by the reaction of corresponding benzaldehydes with a fluorinating agent.