- Crystalline forms of zoledronic acid
-
The invention relates to new crystalline forms of low water soluble salts of zoledronic acid, the process for preparation of these crystalline forms, compositions containing these crystalline forms, and the use of these crystalline forms in diagnostic methods or therapeutic treatment of warm-blooded animals, especially humans. The invention relates to the crystalline form of the free acid monohydrate of zoledronic acid, the process for preparation of the crystalline form of the free acid monohydrate of zoledronic acid, compositions containing the crystalline form of the free acid monohydrate of zoledronic acid, and the use of crystalline form of the free acid monohydrate of zoledronic acid in diagnostic methods or therapeutic treatment of warm-blooded animals, especially humans.
- -
-
Page/Page column 14
(2008/12/05)
-
- A CRYSTALLINE FORM OF THE ZOLEDRONIC ACID, A PROCESS TO OBTAIN IT AND THE PHARMACEUTICAL COMPOSITION COMPRISING IT
-
This invention refers to a new crystalline form of the Zoledronic acid, characterized by its X-rays diffractogram as well as by its spatial atomic distribution in the red crystalline and its curves of thermal analysis. There is also included a method to obtain this crystalline form, which includes the synthesis of the corresponding acid and the pharmaceutical composition this crystalline form comprises.
- -
-
Page/Page column 7-8
(2008/06/13)
-
- CRYSTALLINE TRIHYDRATE OF ZOLEDRONIC ACID
-
Zoledronic acid trihydrate, processes for its preparation, and conversion into zoledronic acid monohydrate.
- -
-
Page/Page column 15
(2008/06/13)
-
- Crystalline form of zoledronic acid
-
Zoledronic acid trihydrate.
- -
-
Page/Page column 4
(2008/06/13)
-
