Substituent effects in the highly regioselective and diastereoselective ene reaction of singlet oxygen with chiral cyclohexadienes
The photooxygenation of the cyclohexadienes 3 and 4, which are readily available through Birch reduction of 2-methylbenzoic acid (1), yielded only one regioisomeric hydroperoxide in a remarkable high diastereoselectivity. A strong directing effect on the