166671-43-8Relevant articles and documents
Benzimidazole condensed ring system. IX. Potential antineoplastics. New synthesis of some pyridobenzimidazoles and related derivatives
Badawey, E.,Kappe, T.
, p. 327 - 332 (2007/10/02)
Some pyridobenzimidazoles were prepared in order to investigate their in vitro antineoplastic and anti-HIV activities.Two compounds (9b, NSC 658526 and 15, NSC 664715) showed a variable degree of antineoplastic activity against some of the cell lines tested.Compound 9a (NSC 649900) exhibited a good in vitro antineoplastic activity with subpanel disease selectivity, particularly against most of the cell lines of leukemia and some cell lines from colon, melanoma and renal cancer panels. 2-acetylbutyrolactone/ pyridobenzimidazole/ antineoplastic activity