16679-95-1

Basic information

• Product Name: Z-TYR-NHNH2
• Synonyms: N-ALPHA-CARBOBENZOXY-L-TYROSINE HYDRAZIDE;Z-L-TYROSINE HYDRAZIDE;Z-TYROSINE-NHNH2;Z-TYR-NHNH2;(S)-BENZYL 1-HYDRAZINYL-3-(4-HYDROXYPHENYL)-1-OXOPROPAN-2-YLCARBAMATE;CBZ-L-TYROSINE HYDRAZIDE
• CAS NO: 16679-95-1
• Molecular Formula: C₁₇H₁₉N₃O₄
• Molecular Weight: 329.35
• Mol File: 16679-95-1.mol

Chemical Properties

• Melting Point: 220 °C
• Boiling Point: 650.4°C at 760 mmHg
• Flash Point: 347.2°C
• Appearance: /
• Density: 1.3g/cm³
• Vapor Pressure: 1.62E-17mmHg at 25°C
• Refractive Index: 1.616
• Storage Temp.: -15°C
• PKA: 9.81±0.15(Predicted)
• CAS DataBase Reference: Z-TYR-NHNH2(CAS DataBase Reference)
• NIST Chemistry Reference: Z-TYR-NHNH2(16679-95-1)
• EPA Substance Registry System: Z-TYR-NHNH2(16679-95-1)

Safety Data

• Hazardous Substances Data: 16679-95-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
Z-TYR-NHNH2 is utilized as a research compound for exploring its potential interactions with biological systems, given its combination of a biologically significant amino acid and a chemically reactive inorganic group. Its role in this context is to aid scientists in understanding how such a compound might influence neurotransmitter pathways or be developed into a therapeutic agent.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, Z-TYR-NHNH2 serves as a starting point for the design and synthesis of new pharmaceuticals. Z-TYR-NHNH2's structure may offer insights into the development of drugs targeting specific receptors or enzymes, particularly those involved in the metabolism of neurotransmitters.
Used in Industrial Processes:
Although not explicitly stated in the provided materials, given that hydrazine is used in various industrial processes, Z-TYR-NHNH2 might also find applications in these areas. However, the specific industrial uses would require further investigation due to the compound's potential health and safety implications related to the hydrazine component.

InChI:InChI=1/C17H19N3O4/c18-20-16(22)15(10-12-6-8-14(21)9-7-12)19-17(23)24-11-13-4-2-1-3-5-13/h1-9,15,21H,10-11,18H2,(H,19,23)(H,20,22)

Upstream product

• 16679-94-0 N-[(phenylmethoxy)carbonyl]-L-tyrosine 
• 13512-31-7 N-(benzyloxycarbonyl)-L-tyrosine methyl ester 
• 86099-14-1 (2S)-3-(4-hydroxyphenyl)-2-(methyl{[(phenylmethyl)oxy]carbonyl}amino)propanoic acid 

Downstream Products

• 67942-47-6 (S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-propionic acid methyl ester 
• 80632-52-6 sulfated [Leu⁵]-enkephalin 
• 130245-55-5 Z-Tyr(SO₃H)-Gly-Gly-Phe-Leu-OBzl 
• 69729-16-4 N-benzyloxycarbonyl-L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucine benzyl ester 
• 139024-47-8 Z-Tyr-Asn-Arg(Mts)-OBzl 
• 139024-51-4 H-Tyr-Asn-Arg-OH 
• 112037-41-9 [(R)-2-(4-Hydroxy-phenyl)-1-isocyanato-ethyl]-carbamic acid benzyl ester 
• 112037-42-0 Z-Tyr-Φ(NHCONH)-Gly-Gly-Phe-Leu-OBzl 
• 95303-43-8 Z-Tyr-Val-Pro-OPFP 
• 112037-33-9 H-Tyr-Φ(NHCONH)-Gly-Gly-Phe-Leu-OH 
• 95303-41-6 Z-Tyr-Val-Pro-OH 
• 95015-82-0 6-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-hexanoic acid phenethyl-amide 
• 95015-77-3 5-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-pentanoic acid phenethyl-amide 
• 95015-81-9 4-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-N-phenethyl-butyramide 

Relevant articles and documents

An efficient, stereocontrolled and versatile synthetic route to bicyclic partially saturated privileged scaffolds

Herein, we describe the development of a simple, high yielding and stereocontrolled strategy for the synthesis of a series of triazolopiperazines and other biologically relevant fused scaffolds from optically active amino acids. This route was applied to the synthesis of 22 scaffolds containing new, previously inaccessible vectors and used to access a novel analogue of ganaplacide.