16726-72-0Relevant articles and documents
Copper-catalysed, diboron-mediated: Cis -dideuterated semihydrogenation of alkynes with heavy water
Han, Xiaowei,Hu, Jiefeng,Chen, Cheng,Yuan, Yu,Shi, Zhuangzhi
supporting information, p. 6922 - 6925 (2019/06/18)
Methods to incorporate deuterium atoms into organic molecules are valuable for the pharmaceutical industry. Here, we found that diboron reagents can efficiently mediate the transfer of two D atoms from heavy water directly onto alkynes through copper-catalysed cis-selective semihydrogenation. Avoiding the use of costly and flammable D2 gas, this safe and practical process can proceed with excellent chemoselectivity and stereoselectivity. Utilizing the present method as the key step, the formal asymmetric total synthesis of d2-deuterium-labeled cis-combretastatin A4 is demonstrated. Mechanistic studies suggest that monoborylation of alkynes is the key step for this semihydrogenation process.
Iron pincer complex catalyzed, environmentally benign, E-selective semi-hydrogenation of alkynes
Srimani, Dipankar,Diskin-Posner, Yael,Ben-David, Yehoshoa,Milstein, David
supporting information, p. 14131 - 14134 (2014/01/06)
Ironing out hydrogenation: For the first time, an iron catalyst provided chemo- and stereo-selective semi-hydrogenation of alkynes to E-alkenes. This efficient, atom-economical reaction is catalyzed by a novel acridine-based PNP iron pincer catalyst and exhibits excellent functional group tolerance under mild, neutral, environmentally benign reaction conditions. Copyright
Photochemical behavior of some p-styrylstilbenes and related compounds: Spectral properties and photoisomerization in solution and in solid state
Fengqiang, Zhu,Motoyoshiya, Jiro,Nakamura, Junji,Nishii, Yoshinori,Aoyama, Hiromu
, p. 1645 - 1650 (2008/02/13)
The spectral properties and Z,E-photoisomerizations of three 4-styrylstilbenes, a 4,4′-bis(β-methylstyryl)benzene and a 4,4′-distyrylstilbene were investigated in solution and in the solid state. Some notable features of the absorption and fluorescence sp
TRANS-CIS PHOTOISOMERIZATION OF PARA-STYRYLSTILBENES
Ito, Yoshikatsu,Uozu, Yoshihiro,Matsuura, Teruo
, p. 3493 - 3496 (2007/10/02)
Quantum yields for trans-cis photoisomerization of trans,trans-para-styrylstilbenes are low from the singlet state (Φ0.1) but high from the triplet state (Φ approx. 0.6).The reaction is moderately regioselective.