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167261-59-8

MDL 105,212 HYDROCHLORIDE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 167261-59-8 Structure

  • Basic information

    1. Product Name: MDL 105,212 HYDROCHLORIDE
    2. Synonyms: MDL 105,212 HYDROCHLORIDE
    3. CAS NO:167261-59-8
    4. Molecular Formula: C34H40Cl3N3O5
    5. Molecular Weight: 677.06
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 167261-59-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: MDL 105,212 HYDROCHLORIDE(CAS DataBase Reference)
    10. NIST Chemistry Reference: MDL 105,212 HYDROCHLORIDE(167261-59-8)
    11. EPA Substance Registry System: MDL 105,212 HYDROCHLORIDE(167261-59-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 167261-59-8(Hazardous Substances Data)

167261-59-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 167261-59-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,7,2,6 and 1 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 167261-59:
(8*1)+(7*6)+(6*7)+(5*2)+(4*6)+(3*1)+(2*5)+(1*9)=148
148 % 10 = 8
So 167261-59-8 is a valid CAS Registry Number.

167261-59-8Downstream Products

167261-59-8Relevant articles and documents

CARBOXYSUBSTITUTED CYCLIC CARBOXAMIDE DERIVATIVES

-

, (2008/06/13)

The present invention relates to novel carboxy substituted cyclic carboxamide derivatives of formula (1), STR1 and stereoisomers and pharmaceutically acceptable salts thereof and their use as tachykinin receptor antagonists. Such antagonists are useful in the treatment of tachykinin-mediated diseases and conditions disclosed herein including: asthma, coughs and bronchitis.

SUBSTITUTED PYRROLIDIN-3-YL-ALKYL-PIPERIDINES

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, (2008/06/13)

The present invention relates to substituted pyrrolidinyl-3-yl-alkyl-piperidines, their stereoisomers, and pharmaceutically acceptable salts thereof and processes for preparation of the same. The compounds of the present invention are useful in their pharmacological activities such as tachykinin antagonism, especially substance P and neurokinin A antagonism, and the like. Compounds having the property of tachykinin antagonism are indicated for conditions associated with neurogenic inflammation and other diseases described herein.

Identification and chemical synthesis of MDL 105,212, a non-peptide tachykinin antagonist with high affinity for NK1 and NK2 receptors

Burkholder, Timothy P.,Kudlacz, Elizabeth M.,Le, Tieu-Binh,Knippenberg, Robert W.,Shatzer, Scott A.,Maynard, George D.,Webster, Mark E.,Horgan, Stephen W.

, p. 951 - 956 (2007/10/03)

We have synthesized and identified MDL 105,212, a non-peptide tachykinin receptor antagonist that has high affinity for human NK1 ((IC50 = 3.11 nM) and NK2 (IC50 = 8.40 nM) receptors. The chemical synthesis of M

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