1,1'-Dicyano-2-substituted ethylenes : A new class of glucose uptake inhibitors in antifilarial chemotherapy
Several 1,1'-dicyano-2-substituted ethylenes (2-16) were synthesized and evaluated for in vivo antifilarial activity. Some of the screened compounds showed significant antifilarial response against Acanthocheilonema viteae in rodents.