16956-53-9 Usage
Uses
Used in Medical Research:
BAPN is used as a research tool for studying the role of lysyl oxidase in connective tissue biology. Its application in this field aids in understanding the mechanisms underlying the crosslinking of collagen and elastin fibers, which are essential for maintaining tissue integrity and function.
Used in Treatment of Fibrosis:
In the medical industry, BAPN is used as a potential therapeutic agent for treating fibrosis, a disease characterized by the excessive accumulation of extracellular matrix proteins, leading to the stiffening and scarring of tissues. By inhibiting lysyl oxidase, BAPN may help reduce the crosslinking of collagen and elastin fibers, thereby mitigating the progression of fibrosis.
Used in Atherosclerosis Treatment:
BAPN is also utilized in the treatment of atherosclerosis, a condition where plaques build up inside the arteries, restricting blood flow. The inhibition of lysyl oxidase by BAPN may contribute to the prevention or reduction of arterial stiffening, which is a key factor in the development of atherosclerosis.
Used in Aneurysm Management:
In the field of cardiovascular medicine, BAPN is explored for its potential role in managing aneurysms, which are abnormal bulges or weaknesses in the blood vessel walls. The inhibition of lysyl oxidase may help in reducing the risk of aneurysm rupture by maintaining the structural integrity of the blood vessel walls.
Used in Bone Density and Tissue Elasticity Studies:
BAPN is employed in research aimed at understanding its effects on bone density and tissue elasticity. [bis(2-hydroxyethyl)amino]methylidenepropanedinitrile's impact on lysyl oxidase activity may provide insights into the regulation of these properties, which are crucial for maintaining the health and function of various tissues and organs in the body.
Check Digit Verification of cas no
The CAS Registry Mumber 16956-53-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,9,5 and 6 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 16956-53:
(7*1)+(6*6)+(5*9)+(4*5)+(3*6)+(2*5)+(1*3)=139
139 % 10 = 9
So 16956-53-9 is a valid CAS Registry Number.
16956-53-9Relevant academic research and scientific papers
1,1'-Dicyano-2-substituted ethylenes : A new class of glucose uptake inhibitors in antifilarial chemotherapy
Tewari, Swati,Chauhan,Bhaduri,Singh,Fatma, Nigar,Chatterjee,Srivastava
, p. 1891 - 1896 (2007/10/03)
Several 1,1'-dicyano-2-substituted ethylenes (2-16) were synthesized and evaluated for in vivo antifilarial activity. Some of the screened compounds showed significant antifilarial response against Acanthocheilonema viteae in rodents.
