An efficient synthesis of 2-[(4-amino-1,2-dihydro-2-oxo-1- pyrimidinyl)methoxy]-1,3-propanediyl-di-L-valinate an anti-cytomegalovirus agent
An efficient synthesis for large scale preparation of the titled compound, a prodrug for the anti-HCMV agent 1-[2-hydroxy-1- (hydroxymethyl)ethoxy)methyl]cytosine, 9, has been developed. The product of each step is easily purified by either distillation o