170856-84-5

Basic information

• Product Name: 3,4-DIHYDRO-1H-2-BENZOPYRAN-1S-ACETIC ACID
• Synonyms: 3,4-DIHYDRO-1H-2-BENZOPYRAN-1S-ACETIC ACID;(1S)-3,4-dihydro-1H-2-Benzopyran-1-acetic acid;(S)-2-(3,4-Dihydro-1H-isochromen-1-yl)acetic acid;(S)-2-(isochroMan-1-yl)acetic acid;(S)-3,4-Dihydro-1H-2-benzopyran-1-acetic acid
• CAS NO: 170856-84-5
• Molecular Formula: C11H12O3
• Molecular Weight: 192.213
• Mol File: 170856-84-5.mol

Chemical Properties

• Boiling Point: 385.3±22.0 °C(Predicted)
• Appearance: /
• Density: 1.205
• Storage Temp.: 2-8°C
• PKA: 4.20±0.10(Predicted)
• CAS DataBase Reference: 3,4-DIHYDRO-1H-2-BENZOPYRAN-1S-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DIHYDRO-1H-2-BENZOPYRAN-1S-ACETIC ACID(170856-84-5)
• EPA Substance Registry System: 3,4-DIHYDRO-1H-2-BENZOPYRAN-1S-ACETIC ACID(170856-84-5)

Safety Data

• Hazardous Substances Data: 170856-84-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3,4-Dihydro-1H-2-benzopyran-1S-acetic acid is used as a pharmaceutical compound for its potential health benefits. It is believed to have antioxidant and anti-inflammatory properties, which may contribute to the prevention of cancer and cardiovascular diseases.
Used in Nutraceutical Industry:
In the nutraceutical industry, 3,4-Dihydro-1H-2-benzopyran-1S-acetic acid is used as a dietary supplement or functional food ingredient due to its potential health-promoting properties. Its antioxidant and anti-inflammatory effects may support overall health and well-being.
Used in Cosmetic Industry:
3,4-Dihydro-1H-2-benzopyran-1S-acetic acid is used as an active ingredient in cosmetic products for its potential skin health benefits. Its antioxidant properties may help protect the skin from environmental damage, while its anti-inflammatory effects may soothe and calm irritated skin.
Used in Material Science:
In the field of material science, 3,4-Dihydro-1H-2-benzopyran-1S-acetic acid may have potential applications in the development of new materials. Its unique chemical structure and properties could be utilized to create innovative materials with specific characteristics for various industries.

Upstream product

• 22901-11-7 (isochroman-1-yl)acetic acid 
• 170856-55-0 ethyl 2-(isochroman-1-yl)acetate 
• 60-12-8 2-phenylethanol 
• 1032509-36-6 isopropyl 2-(3,4-dihydro-1H-isochromen-1-yl)acetate 

Downstream Products

• 177742-21-1 (S)-2-(isochroman-1-yl)ethan-1-ol 
• 177742-20-0 (R)-(+)-α-(β-hydroxyethyl)isochroman 
• 1338236-57-9 (R)-1-phenethyl-3,4-dihydro-1H-isochromene 
• 1338236-52-4 (S)-1-phenethyl-3,4-dihydro-1H-isochromene 
• 170858-33-0 sonepiprazole 

Relevant articles and documents

Copper-catalyzed enantioselective additions to oxocarbenium ions: Alkynylation of isochroman acetals

We have developed an enantioselective, copper(I)-catalyzed addition of terminal alkynes to racemic isochroman acetals. This method is one of the first transition-metal-catalyzed approaches to enantioselective additions to prochiral oxocarbenium ions. In this reaction, TMSOTf is used to form the oxocarbenium ion in situ under conditions compatible with simultaneous formation of the chiral copper acetylide. By using a bis(oxazoline) ligand, good yields and enantioselectivities are observed for a variety of enantioenriched 1-alkynyl isochromans.

Enantioselective thiourea-catalyzed additions to oxocarbenium ions

Asymmetric, catalytic reactions of oxocarbenium ions are reported. Simple, chiral urea and thiourea derivatives are shown to catalyze the enantioselective substitution of silyl ketene acetals onto 1-chloroisochromans. A mechanism involving anion binding by the chiral catalyst to generate a reactive oxocarbenium ion is invoked. Catalysts bearing tertiary benzylic amide groups afforded highest enantioselectivities, with the optimal structure being derived from enantioenriched 2-arylpyrrolidine derivatives. Copyright