Gramine Derivatives Targeting Ca2+ Channels and Ser/Thr Phosphatases: A New Dual Strategy for the Treatment of Neurodegenerative Diseases
We describe the synthesis of gramine derivatives and their pharmacological evaluation as multipotent drugs for the treatment of Alzheimer's disease. An innovative multitarget approach is presented, targeting both voltage-gated Ca2+ channels, cl
Lajarín-Cuesta, Rocío,Nanclares, Carmen,Arranz-Tagarro, Juan-Alberto,González-Lafuente, Laura,Arribas, Raquel L.,Araujo De Brito, Monique,Gandía, Luis,De Los Ríos, Cristóbal
p. 6265 - 6280
(2016/07/26)
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