The present invention relates to novel pyrimidine acyclonucleoside derivatives represented by the following general formula (I), antiviral agents containing the derivatives as the active ingredients and processes of preparation thereof. STR1 wherein Rsup
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(2008/06/13)
Synthesis and anti-HIV-1 activity of a series of 1-(alkoxymethyl)-5-alkyl-6-(arylselenenyl)uracils and -2-thiouracils
A series of 1-(alkoxymethyl)-5-alkyl-6-(phenylselenenyl)uracils and -2-thiouracils modified at the 3- and/or 5-posiuon of the C-6 phenylselenenyl ring with methyl or fluoro substituent has been synthesized and tested for their ability to inhibit HIV-1 rep
Kim, Dae-Kee,Kim, Young-Woo,Gam, Jongsik,Kim, Ganghyeok,Lim, Jinsoo,Lee, Namkyu,Kim, Hun-Taek,Kim, Key H.
p. 1275 - 1283
(2007/10/03)
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