- Synthesis method of 7-methyltryptophan
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The invention provides a synthesis method of 7-methyl tryptophan, which comprises the following steps: (1) reacting a compound a with a compound b to obtain a compound 1; (2) reacting the compound 1 with water to obtain a compound 2; (3) reacting the compound 2 with hydrogen to obtain a compound 3; and (4) carrying out hydrolysis reaction on the compound 3 to obtain the 7-methyl tryptophan. The method has the advantages of cheap and accessible raw materials, mild reaction conditions, simple equipment requirements and high safety index, and is suitable for large-scale commercial production. Thetotal yield of the 7-methyl tryptophan prepared by the method is as high as 52.6%, and the purity of the 7-methyl tryptophan is as high as 98%. The invention provides a new choice for the commercialproduction process of the 7-methyl tryptophan medicinal intermediate.
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