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7-Methyl-DL-Tryptophan, also known as 1-Methyl-DL-Tryptophan or Indoximod, is a derivative of the essential amino acid tryptophan that is often used in studies related to immunology and cancer treatment. It is recognized as an immunomodulatory drug that has the potential to hinder specific enzymes, regulating the immune response against cancer cells.

17332-70-6

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17332-70-6 Usage

Uses

Used in Cancer Treatment:
7-Methyl-DL-Tryptophan is used as an immunomodulatory drug for inhibiting the indoleamine 2,3-dioxygenase (IDO) pathway, which is involved in the regulation of immune response and tumor growth. This application is particularly relevant in numerous types of cancers, where it has been shown to suppress tumor growth and enhance the effectiveness of other cancer treatments.
Used in Preclinical and Clinical Studies:
7-Methyl-DL-Tryptophan is used as a research compound for investigating its effects on the immune system and its potential role in cancer treatment. It is frequently administered orally in these studies, allowing researchers to assess its safety, efficacy, and optimal dosing strategies.
Used in Immunology Research:
7-Methyl-DL-Tryptophan is used as a tool in immunology research to understand the mechanisms by which it modulates the immune response. This knowledge can contribute to the development of new therapeutic strategies for various diseases, including cancer, by targeting specific enzymes and pathways involved in immune regulation.

Check Digit Verification of cas no

The CAS Registry Mumber 17332-70-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,3,3 and 2 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 17332-70:
(7*1)+(6*7)+(5*3)+(4*3)+(3*2)+(2*7)+(1*0)=96
96 % 10 = 6
So 17332-70-6 is a valid CAS Registry Number.
InChI:InChI=1/C12H14N2O2/c1-7-3-2-4-9-8(6-14-11(7)9)5-10(13)12(15)16/h2-4,6,10,14H,5,13H2,1H3,(H,15,16)/t10-/m0/s1

17332-70-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-amino-3-(7-methyl-1H-indol-3-yl)propanoic acid

1.2 Other means of identification

Product number -
Other names 7-Methyl-tryptophan

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17332-70-6 SDS

17332-70-6Downstream Products

17332-70-6Relevant articles and documents

Synthesis method of 7-methyltryptophan

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, (2020/12/30)

The invention provides a synthesis method of 7-methyl tryptophan, which comprises the following steps: (1) reacting a compound a with a compound b to obtain a compound 1; (2) reacting the compound 1 with water to obtain a compound 2; (3) reacting the compound 2 with hydrogen to obtain a compound 3; and (4) carrying out hydrolysis reaction on the compound 3 to obtain the 7-methyl tryptophan. The method has the advantages of cheap and accessible raw materials, mild reaction conditions, simple equipment requirements and high safety index, and is suitable for large-scale commercial production. Thetotal yield of the 7-methyl tryptophan prepared by the method is as high as 52.6%, and the purity of the 7-methyl tryptophan is as high as 98%. The invention provides a new choice for the commercialproduction process of the 7-methyl tryptophan medicinal intermediate.

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