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CAS

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173952-44-8

(+/-)-4-(4-AMINOPHENYL)-1,2-DIHYDRO-1-METHYL-2-PROPYLCARBAMOYL-6,7-METHYLENEDIOXYPHTHALAZINE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 8-(4-aminophenyl)-5-methyl-N-propyl-2H,5H-[1,3]dioxolo[4,5-g]phthalazine-6-carboxamide

    Cas No: 173952-44-8

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  • 173952-44-8 Structure

  • Basic information

    1. Product Name: (+/-)-4-(4-AMINOPHENYL)-1,2-DIHYDRO-1-METHYL-2-PROPYLCARBAMOYL-6,7-METHYLENEDIOXYPHTHALAZINE
    2. Synonyms: SYM 2206;(+/-)-4-(4-AMINOPHENYL)-1,2-DIHYDRO-1-METHYL-2-PROPYLCARBAMOYL-6,7-METHYLENEDIOXYPHTHALAZINE;8-(4-Aminophenyl)-5-methyl-N-propyl-1,3-dioxolo[4,5-g]phthalazine-6(5H)-carboxamide;1,3-Dioxolo[4,5-g]phthalazine-6(5H)-carboxamide, 8-(4-aminophenyl)-5-methyl-N-propyl-
    3. CAS NO:173952-44-8
    4. Molecular Formula: C20H22N4O3
    5. Molecular Weight: 366.41
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 173952-44-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: °Cat760mmHg
    3. Flash Point: °C
    4. Appearance: /
    5. Density: 1.37g/cm3
    6. Refractive Index: 1.673
    7. Storage Temp.: Store at RT
    8. Solubility: N/A
    9. CAS DataBase Reference: (+/-)-4-(4-AMINOPHENYL)-1,2-DIHYDRO-1-METHYL-2-PROPYLCARBAMOYL-6,7-METHYLENEDIOXYPHTHALAZINE(CAS DataBase Reference)
    10. NIST Chemistry Reference: (+/-)-4-(4-AMINOPHENYL)-1,2-DIHYDRO-1-METHYL-2-PROPYLCARBAMOYL-6,7-METHYLENEDIOXYPHTHALAZINE(173952-44-8)
    11. EPA Substance Registry System: (+/-)-4-(4-AMINOPHENYL)-1,2-DIHYDRO-1-METHYL-2-PROPYLCARBAMOYL-6,7-METHYLENEDIOXYPHTHALAZINE(173952-44-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 173952-44-8(Hazardous Substances Data)

173952-44-8 Usage

Uses

SYM 2206 is a potent, selective and noncompetitive AMPA receptor inhibitor.

Biological Activity

Novel, potent, non-competitive AMPA receptor antagonist (IC 50 = 2.8 μ M ). Acts allosterically at the same regulatory site as GYKI 52466 and 53655 and other benzodiazepines but does not bind to the central diazepine binding site. Selective for AMPA relative to kainate receptor sub-types. Similar potency to GYKI 53655. Anticonvulsant in vivo .

Check Digit Verification of cas no

The CAS Registry Mumber 173952-44-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,3,9,5 and 2 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 173952-44:
(8*1)+(7*7)+(6*3)+(5*9)+(4*5)+(3*2)+(2*4)+(1*4)=158
158 % 10 = 8
So 173952-44-8 is a valid CAS Registry Number.
InChI:InChI=1/C20H22N4O3/c1-3-8-22-20(25)24-12(2)15-9-17-18(27-11-26-17)10-16(15)19(23-24)13-4-6-14(21)7-5-13/h4-7,9-10,12H,3,8,11,21H2,1-2H3,(H,22,25)

173952-44-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name SYM 2206,(±)-4-(4-Aminophenyl)-1,2-dihydro-1-methyl-2-propylcarbamoyl-6,7-methylenedioxyphthalazine

1.2 Other means of identification

Product number -
Other names TRIS hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:173952-44-8 SDS

173952-44-8Downstream Products

173952-44-8Relevant articles and documents

Dihydrophthalazine antagonists of excitatory amino acid receptors

-

, (2008/06/13)

Substituted dihydrophthalazine compositions are provided which are active as non-NMDA ionotropic excitatory amino acid (EAA) receptor antagonists. The compositions are useful for treating disorders associated with excessive activation of the non-NMDA subt

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