175394-01-1

Basic information

• Product Name: ETHYL 4-(3,4-DIMETHYLPHENYL)-4-OXOBUTYRATE
• Synonyms: ETHYL 4-(3,4-DIMETHYLPHENYL)-4-OXOBUTYRATE
• CAS NO: 175394-01-1
• Molecular Formula: C₁₄H₁₈O₃
• Molecular Weight: 234.29
• Mol File: 175394-01-1.mol

Chemical Properties

• Boiling Point: 361.9°C at 760 mmHg
• Flash Point: 158.8°C
• Appearance: /
• Density: 1.05g/cm³
• Vapor Pressure: 2E-05mmHg at 25°C
• Refractive Index: 1.505
• CAS DataBase Reference: ETHYL 4-(3,4-DIMETHYLPHENYL)-4-OXOBUTYRATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 4-(3,4-DIMETHYLPHENYL)-4-OXOBUTYRATE(175394-01-1)
• EPA Substance Registry System: ETHYL 4-(3,4-DIMETHYLPHENYL)-4-OXOBUTYRATE(175394-01-1)

Safety Data

• Hazardous Substances Data: 175394-01-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H18O3/c1-4-17-14(16)8-7-13(15)12-6-5-10(2)11(3)9-12/h5-6,9H,4,7-8H2,1-3H3

Upstream product

• 14794-31-1 ethyl 3-(chloroformyl)propionate 
• 95-47-6 o-xylene 

Downstream Products

• 905590-57-0 4-(3,4-dimethylphenyl)-4,4-dimethoxybutanoic acid potassium salt 
• 51036-98-7 3-(3,4-dimethylbenzoyl)propionic acid 

Relevant articles and documents

AMIDE COMPOUND

The present invention relate to a compound represented by the formula (I) or (II) wherein ring A is an optionally substituted ring (the ring should not be pyrrolidine, piperidine and piperazine), ring B is an optionally substituted aromatic ring, ring D is an optionally substituted ring, R1 and R2 are each independently a hydrogen atom or a substituent, R3 is a hydrogen atom or a C1-6 alkyl group, or R3 is bonded to ring A to form a non-aromatic ring, ring Aa is an optionally substituted aromatic hydrocarbon, Y is CH or N, Ra1 is an optionally substituted hydrocarbon group, and Ra2 and Ra3 are each independently a hydrogen atom or a substituent, or a salt thereof. The present invention provides a compound having a DGAT inhibitory activity, which is useful for the treatment or amelioration of diseases or pathologies caused by high expression or high activation of DGAT.

AMIDE COMPOUND

Disclosed is a compound represented by the formula (I) or (II) below, or a salt thereof. [In the formulae, ring A represents an optionally substituted ring (which is not a pyrrolidine, piperidine or piperazine); ring B represents an optionally substituted aromatic ring; ring D represents an optionally substituted ring; R1 and R2 independently represent a hydrogen atom or a substituent; R3 represents a hydrogen atom or a C1-6 alkyl group, or alternatively it combines with the ring A to form a non-aromatic ring; ring Aa represents an optionally substituted aromatic hydrocarbon; Y represents CH or N; Ra1 represents an optionally substituted hydrocarbon group; and Ra2 and Ra3 independently represent a hydrogen atom or a substituent.] The compound has a DGAT inhibitory effect and is useful for treatment or improvement of diseases or conditions caused by high expression or high activation of DGAT.

Phosphonic acid compounds, their production and use

The present invention relates to a compound of the general formula (I): STR1 wherein ring A is a benzene ring that may be substituted; Y is a divalent group as a constituent member of ring B forming a 5- to 8-membered ring; Q1 is a group of the formula --X--P(O)(OR1)(OR2) wherein X is a bond or a divalent group; R1 and R2, identical or different, are hydrogen or a lower alkyl, or may be combined together to form a ring; Q2 is hydrogen, a hydrocarbon group that may be substituted or a heterocyclic group that may be substituted; and the group of the formula --CON(Q1)(Q2) is connected to the a- or b-position carbon atom, or a salt thereof, which is useful as prophylactic and therapeutic agents of various metabolic bone diseases such as osteoporosis.