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4-Fluoro-2-(trifluoromethyl)-benzenesulfonyl chloride is a unique chemical compound with the formula C7H3ClF4O2S. It belongs to the class of benzenes, specifically benzene and its substituted derivatives. This organic substance features a benzene ring, a sulfonyl chloride group, and several fluorine atoms. The presence of fluorine atoms and the sulfonyl chloride group makes it a highly reactive compound. Often used in various chemical synthesis processes, this compound may act as an electrophile that can engage in chemical reactions with nucleophiles. However, due to its reactive nature, interactions must be managed under controlled conditions to minimize the risk of generating toxic byproducts. Overall, it's an important compound utilized in the field of organic chemistry.

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  • 176225-09-5 Structure
  • Basic information

    1. Product Name: 4-FLUORO-2-(TRIFLUOROMETHYL)-BENZENESULFONYL CHLORIDE
    2. Synonyms: 4-Ffloro-2-(trifluoromethyl)-benzenesulfonylchloride;4-Fluoro-2-(trifluoromethyl)benzenesulfonyl chloride, 97+%;2-(Chlorosulphonyl)-4-fluorobenzotrifluoride;4-Fluoro-2-(trifluoroMethyl)benzene-1-sulfonyl chloride;2-(Chlorosulphonyl)-5-fluorobenzotrifluoride;4-Fluoro-2-(trifluoroMethyl)benzenesulfonyl chloride 97%;4-Fluoro-2-(trifluoromethyl)benzenesulphonylchloride98%
    3. CAS NO:176225-09-5
    4. Molecular Formula: C7H3ClF4O2S
    5. Molecular Weight: 262.61
    6. EINECS: N/A
    7. Product Categories: Fluorine series
    8. Mol File: 176225-09-5.mol
  • Chemical Properties

    1. Melting Point: 54-56°C
    2. Boiling Point: 76°C/0.5mm
    3. Flash Point: >110℃
    4. Appearance: /
    5. Density: 1.603g/cm3
    6. Vapor Pressure: 0.0125mmHg at 25°C
    7. Refractive Index: 1.467
    8. Storage Temp.: Inert atmosphere,Room Temperature
    9. Solubility: soluble in Methanol
    10. Sensitive: Moisture Sensitive
    11. CAS DataBase Reference: 4-FLUORO-2-(TRIFLUOROMETHYL)-BENZENESULFONYL CHLORIDE(CAS DataBase Reference)
    12. NIST Chemistry Reference: 4-FLUORO-2-(TRIFLUOROMETHYL)-BENZENESULFONYL CHLORIDE(176225-09-5)
    13. EPA Substance Registry System: 4-FLUORO-2-(TRIFLUOROMETHYL)-BENZENESULFONYL CHLORIDE(176225-09-5)
  • Safety Data

    1. Hazard Codes: Xi,C
    2. Statements: 34
    3. Safety Statements: 36/37/39-26
    4. RIDADR: UN3261
    5. WGK Germany: 3
    6. RTECS:
    7. HazardClass: 8
    8. PackingGroup: II
    9. Hazardous Substances Data: 176225-09-5(Hazardous Substances Data)

176225-09-5 Usage

Uses

Used in Organic Chemistry Synthesis:
4-Fluoro-2-(trifluoromethyl)-benzenesulfonyl chloride is used as a reactive intermediate for the synthesis of various organic compounds. Its reactivity as an electrophile allows it to participate in chemical reactions with nucleophiles, leading to the formation of new molecules with potential applications in different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-fluoro-2-(trifluoromethyl)-benzenesulfonyl chloride is used as a key building block for the development of new drugs. Its unique molecular structure can be incorporated into drug molecules to enhance their therapeutic properties, such as improving their potency, selectivity, or bioavailability.
Used in Material Science:
4-Fluoro-2-(trifluoromethyl)-benzenesulfonyl chloride is used as a precursor in the synthesis of advanced materials, such as polymers and coatings, with specific properties tailored for various applications. Its incorporation into these materials can lead to improved performance characteristics, such as increased stability, durability, or resistance to environmental factors.
Used in Agrochemical Industry:
In the agrochemical industry, 4-fluoro-2-(trifluoromethyl)-benzenesulfonyl chloride is used as a starting material for the synthesis of new pesticides or herbicides. Its reactivity and molecular structure can be exploited to create compounds with enhanced efficacy and selectivity, leading to more effective crop protection strategies.

Check Digit Verification of cas no

The CAS Registry Mumber 176225-09-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,6,2,2 and 5 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 176225-09:
(8*1)+(7*7)+(6*6)+(5*2)+(4*2)+(3*5)+(2*0)+(1*9)=135
135 % 10 = 5
So 176225-09-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H3ClF4O2S/c8-15(13,14)6-2-1-4(9)3-5(6)7(10,11)12/h1-3H

176225-09-5 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
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  • Alfa Aesar

  • (H26637)  4-Fluoro-2-(trifluoromethyl)benzenesulfonyl chloride, 97%   

  • 176225-09-5

  • 250mg

  • 687.0CNY

  • Detail
  • Alfa Aesar

  • (H26637)  4-Fluoro-2-(trifluoromethyl)benzenesulfonyl chloride, 97%   

  • 176225-09-5

  • 1g

  • 1754.0CNY

  • Detail
  • Aldrich

  • (714496)  4-Fluoro-2-(trifluoromethyl)benzenesulfonylchloride  97%

  • 176225-09-5

  • 714496-1G

  • 624.78CNY

  • Detail

176225-09-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Fluoro-2-(trifluoromethyl)benzene-1-sulfonyl chloride

1.2 Other means of identification

Product number -
Other names 4-fluoro-2-(trifluoromethyl)benzenesulfonyl chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:176225-09-5 SDS

176225-09-5Relevant articles and documents

N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1

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Page/Page column 84, (2008/12/05)

Compounds of formula (I): Chemical formula should be inserted here as it appears on the abstract in paper form. and pharmaceutically acceptable salt thereof, which are modulators of secreted frizzled related protein-1, are disclosed. The compounds, and co

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