17721-00-5 Usage
Uses
Used in Pharmaceutical Industry:
5-Thiazolamine is used as an active pharmaceutical ingredient for its antibacterial and antifungal properties, contributing to the development of new drugs to combat resistant infections. Its antioxidant and anti-inflammatory properties also make it a promising candidate for the treatment of inflammatory and oxidative stress-related disorders.
Used in Agrochemical Industry:
In the agrochemical sector, 5-Thiazolamine is utilized as a bioactive component in the formulation of fungicides and bactericides. Its ability to inhibit the growth of harmful microorganisms protects crops and enhances agricultural productivity.
Used in Medicinal Chemistry Research:
5-Thiazolamine serves as a key intermediate in the synthesis of various medicinal compounds. Its unique structure and reactivity facilitate the development of novel therapeutic agents with potential applications in diverse medical fields.
Used in Antioxidant and Anti-Inflammatory Applications:
Due to its antioxidant and anti-inflammatory properties, 5-Thiazolamine is employed in the development of agents aimed at mitigating oxidative stress and inflammation, which are implicated in numerous pathological conditions.
Used in Scientific Research:
5-Thiazolamine's diverse biological activities and chemical reactivity make it an important tool in scientific research, particularly in studies focused on understanding the mechanisms of action of various drugs and exploring new therapeutic targets.
Check Digit Verification of cas no
The CAS Registry Mumber 17721-00-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,7,2 and 1 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 17721-00:
(7*1)+(6*7)+(5*7)+(4*2)+(3*1)+(2*0)+(1*0)=95
95 % 10 = 5
So 17721-00-5 is a valid CAS Registry Number.
InChI:InChI=1/C3H4N2S.ClH/c4-3-1-5-2-6-3;/h1-2H,4H2;1H
17721-00-5Relevant articles and documents
Pyridyl and thiazolyl bisamide CSF-1R inhibitors for the treatment of cancer
Scott, David A.,Aquila, Brian M.,Bebernitz, Geraldine A.,Cook, Donald J.,Dakin, Les A.,Deegan, Tracy L.,Hattersley, Maureen M.,Ioannidis, Stephanos,Lyne, Paul D.,Omer, Charles A.,Ye, Minwei,Zheng, XiaoLan
scheme or table, p. 4794 - 4797 (2009/05/30)
The bisamide class of kinase inhibitors was identified as being active against CSF-1R. The synthesis and SAR of pyridyl and thiazolyl bisamides are reported, along with the pharmacokinetic properties and in vivo activity of selected examples.
Mechanism of azo coupling reactions. Part 34. Reactivity of five-membered ring heteroaromatic diazonium ions
Diener, Heinz,Zollinger, Heinrich
, p. 1102 - 1107 (2007/10/02)
The azo coupling reactions of six five-membered heteroaromatic diazonium ions with 2-naphthol-3,6-disulfonic acid are investigated kinetically at various pH values.The dependence of the measured rate constants on the acidity of the aqueous reaction system is evaluated.It can be shown that the 2-naphtholate-3,6-disulfonate trianion reacts 4E8 - 8E8 times faster than the 2-naphthol-3,6-disulfonate dianion.The rate constants of the six diazonium ions vary by more than four orders of magnitude.The logarithms of the rate constants of all comparable diazonium ions correlate linearly with 1H-nmr chemical shifts of the respective unsubstituted heteroaromatic parent compounds.An analogous correlation was found for azo couplings with substituted benzenediazonium ions.Diazotization of heteroaromatic amines does not go to completion, rather to an equilibrium.It is shown therefore that in acidic coupling systems the azo compound is only the kinetically controlled product.The thermodynamic products are 1-nitroso-2-naphthol-3,6-disulfonic acid and the heteroaromatic amine.
