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6-Methyl-imidazo[1,2-a]pyrazine-2-carboxylic acid ethyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 177842-80-7 Structure
  • Basic information

    1. Product Name: 6-Methyl-imidazo[1,2-a]pyrazine-2-carboxylic acid ethyl ester
    2. Synonyms: 6-Methyl-imidazo[1,2-a]pyrazine-2-carboxylic acid ethyl ester
    3. CAS NO:177842-80-7
    4. Molecular Formula: C10H11N3O2
    5. Molecular Weight: 205.21324
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 177842-80-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 6-Methyl-imidazo[1,2-a]pyrazine-2-carboxylic acid ethyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: 6-Methyl-imidazo[1,2-a]pyrazine-2-carboxylic acid ethyl ester(177842-80-7)
    11. EPA Substance Registry System: 6-Methyl-imidazo[1,2-a]pyrazine-2-carboxylic acid ethyl ester(177842-80-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 177842-80-7(Hazardous Substances Data)

177842-80-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 177842-80-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,7,8,4 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 177842-80:
(8*1)+(7*7)+(6*7)+(5*8)+(4*4)+(3*2)+(2*8)+(1*0)=177
177 % 10 = 7
So 177842-80-7 is a valid CAS Registry Number.

177842-80-7Relevant articles and documents

HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS

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Paragraph 000155; 000156, (2019/06/11)

The compounds of Formula I, Formula Ia, and Formula Ib are described herein along with their analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites, and prodrugs thereof. These compounds inhibit PRMT5 and are useful as therpeautic or ameliorating agent for diseases that are involved in cellular growth such as malignant tumors, schizophrenia, Alzheimer's disease, Parkinson's disease and the like.

COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY

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Paragraph 001201; 001202, (2013/08/28)

Provided herein are compounds, compositions thereof and uses therewith for treating spinal muscular atrophy.

Research on heterocyclic compounds. XXXVII. Synthesis and antiinflammatory activity of methyl-substituted imidazo[1,2-a]pyrazine derivatives

Rimoli,Avallone,De Caprariis,Luraschi,Abignente,Filippelli,Berrino,Rossi

, p. 195 - 203 (2007/10/03)

A series of methyl-substituted imidazo[1,2-a]pyrazines 8 bearing a carboxylic acid group on the imidazole ring were synthesized. The structures of new compounds were confirmed by 1H- and 13C-NMR spectral data; the correct assignment of carbon resonances was made by means of HETCOR and COLOC experiments. Antiinflammatory, analgesic and ulcerogenic activities in vivo were evaluated and compared with those of antiinflammatory imidazopyrazines (2 and 3) and indomethacin. The inhibitory action on cyclooxygenase activity was evaluated in vitro. Compounds 8 were found to be less potent than indomethacin in these assays. SARs are discussed.

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