17809-36-8

Basic information

• Product Name: 2-FLUORO-6-NITRO-PHENYLAMINE
• Synonyms: 2-FLUORO-6-NITROANILINE;2-FLUORO-6-NITRO-PHENYLAMINE;2-Fluoro-6-Nitroaniline/2-Amino-3-Nitrofluorobenzene;2-Fluoro-6-nitroaniline 98%;2-Fluoro-6-nitroaniline98%;2-Nitro-6-fluoroaniline;Einecs 241-779-9;2-Amino-3-fluoronitrobenzene
• CAS NO: 17809-36-8
• Molecular Formula: C₆H₅FN₂O₂
• Molecular Weight: 156.11
• EINECS: 241-779-9
• Product Categories: Miscellaneous;Benzenes
• Mol File: 17809-36-8.mol

Chemical Properties

• Melting Point: 74-75
• Boiling Point: 271.5 °C at 760 mmHg
• Flash Point: 118 °C
• Appearance: /
• Density: 1.448 g/cm³
• Vapor Pressure: 0.00644mmHg at 25°C
• Refractive Index: 1.603
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -1.76±0.25(Predicted)
• CAS DataBase Reference: 2-FLUORO-6-NITRO-PHENYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FLUORO-6-NITRO-PHENYLAMINE(17809-36-8)
• EPA Substance Registry System: 2-FLUORO-6-NITRO-PHENYLAMINE(17809-36-8)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 17809-36-8(Hazardous Substances Data)

Usage

Chemical Properties

light yellow powder

InChI:InChI=1/C6H5FN2O2/c7-4-2-1-3-5(6(4)8)9(10)11/h1-3H,8H2

Upstream product

• 342-52-9 N-(2-fluoro-6-nitrophenyl)acetamide 
• 124-41-4 sodium methylate 
• 402-67-5 3-fluoro-1-nitrobenzene 
• 21397-07-9 2-chloro-3-fluoro-nitrobenzene 
• 399-31-5 N-(2-fluorophenyl)acetamide 
• 348-54-9 2-Fluoroaniline 

Downstream Products

• 21325-05-3 1-fluoro-3-nitro-2-thiocyanatobenzene 
• 1400820-23-6 C₂₈H₂₁FN₅O₂P 
• 1417898-53-3 7-fluoro-4-N,N-dimethylaminosulfonyl-2,1,3-benzothiadiazole 
• 182551-18-4 2-fluoro-N-methyl-6-nitroaniline 
• 1482558-25-7 4-chloro-2-fluoro-6-nitrobenzenamine 
• 111721-75-6 2-bromo-3-fluoroaniline 
• 851368-08-6 1-bromo-2-fluoro-6-iodobenzene 

Relevant articles and documents

Design, synthesis and antitubercular activity of 4-alkoxy-triazoloquinolones able to inhibit the M. tuberculosis DNA gyrase

A number of new F-triazolequinolones (FTQs) and alkoxy-triazolequinolones (ATQs) were designed, synthesized and evaluated for their activity against Mycobacterium tuberculosis H37Rv. Five out of 21 compounds exhibited interesting minimum inhibitory concen

Preparation method of 2 - fluorine -6 - nitroaniline

The invention discloses a preparation method of 2 -fluoro -6 - nitroaniline, and the specific steps of the preparation method are as follows: (1) taking M-fluoronitrobenzene as a starting raw material, reacting with hexachloroethane under the catalysis condition of tert-butyl alcohol lithium III, and reacting with hexachloroethane. (2) Compound III amine is hydrolyzed to give compound I. That is, the 2 - fluorine -6 - nitroaniline. To the invention, a large amount of easily toxic and easily-produced reagents are avoided in the full synthetic route process taking the meta-fluoronitrobenzene as a starting raw material, and the raw materials are low in price.

Synthesis and Evaluation of Novel 7- and 8-Aminophenoxazinones for the Detection of β-Alanine Aminopeptidase Activity and the Reliable Identification of Pseudomonas aeruginosa in Clinical Samples

A series of novel 8-aminophenoxazin-3-one and 7-aminophenoxazin-3-one chromogens and their corresponding β-alanine derivatives were synthesized and evaluated for their ability to detect β-alanyl aminopeptidase activity in bacteria known to hydrolyze β-ala

Fluorinated Fe(III) salophene complexes: Optimization of tumor cell specific activity and utilization of fluorine labeling for in vitro analysis

Fluorine-substituted iron(III) salophene complexes (salophene = N,N'-bis(salicylidene)-1,2-phenylenediamine) were synthesized and evaluated for biological activity. All complexes showed growth inhibitory effects with IC50 values ranging from 0.

New fluorogenic benzothiadiazole and benzoselenadiazole reagents to yield environment-sensitive fluorophores via a reaction with amines

We introduce 7-fluoro-4-N,N-dimethylaminosulfonyl-2,1,3-benzothiadiazole and 7-fluoro-4-N,N-dimethylaminosulfonyl-2,1,3-benzoselenadiazole as new fluorogenic reagents for amines. These reagents are nonfluorescent themselves and can easily react with nonfl

A convenient copper-catalyzed direct animation of nitroarenes with 9-alkylhydroxylamines

O-Alkylhydroxylamines, particularly O-methylhydroxylamine, aminate nitroarenes in the presence of a strong base and a copper catalyst to give aminonitroarenes in good yields, ortho- or para-Animation with respect to the nitro group takes place, and in some cases the ortho-aminated product is preferentially obtained. With 3-substituted nitrobenzenes where the substituent has a lone pair of electrons, preferential amination occurs at the 2-position to give the sterically most congested 3c-f, 14 and 22g.

HETEROCYCLIC SYSTEMS CONTAINING BRIDGEHEAD NITROGEN ATOM: PART LXVI. STUDIES OF ORIENTATION OF CYCLIZATION IN THE SYNTHESIS OF 8-FLUOROTHIAZOLOBENZIMIDAZOL-3(2H)-ONE

2-Fluoro-6-nitroaniline, obtained by nitration of 2-fluoroacetanilide, on reduction with Raney nickel and hydrazine hydrate followed by treatment of the resulting diamine with carbon disulphide in situ gives 4-fluorobenzimidazolyl-2-thione.This thione on condensation with chloroacetic acid gives 4-fluorobenzimidazol-2-thiolacetic acid which on cyclization with a mixture of acetic anhydride and pyridine furnished 8-fluorothiazolobenzimidazol-3(2H)-one as revealed by 1H-NMR spectroscopy.The condensation of 4-fluorobenzimidazolyl-2-thione with 1,2-dibromoethane yields 2,3-dihydro-8-fluorothiazolobenzimidazole and sym-bis-(4-fluorobenzimidazol-2-ylmercapto)ethane.