178429-67-9

Basic information

• Product Name: 4-(4-Fluorophenyl)-2-methyl-6-[5-(1-piperidinyl)pentyloxy]pyrimidine hydrochloride
• Synonyms: Enecadin hydrochloride; NS-7
• CAS NO: 178429-67-9
• Molecular Formula: C₂₁H₂₈FN₃O*ClH
• Molecular Weight: 393.93618
• Mol File: 178429-67-9.mol

Chemical Properties

• CAS DataBase Reference: 4-(4-Fluorophenyl)-2-methyl-6-[5-(1-piperidinyl)pentyloxy]pyrimidine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Fluorophenyl)-2-methyl-6-[5-(1-piperidinyl)pentyloxy]pyrimidine hydrochloride(178429-67-9)
• EPA Substance Registry System: 4-(4-Fluorophenyl)-2-methyl-6-[5-(1-piperidinyl)pentyloxy]pyrimidine hydrochloride(178429-67-9)

Safety Data

• Hazardous Substances Data: 178429-67-9(Hazardous Substances Data)

Upstream product

• 2937-83-9 5-(1-piperidyl)-1-pentanol 
• 178430-13-2 4-chloro-6-(4-fluorophenyl)-2-methylpyrimidine 

Relevant articles and documents

PROCESS FOR PRODUCING PYRIMIDINE DERIVATIVE AND INTERMEDIATE THEREOF

The present invention relates to a method for producing a pyrimidine derivative useful as a neurocyte necrosis inhibitor and an intermediate thereof. More particularly speaking, a method for producing an acid salt of 4-(4-fluorophenyl)-2-methyl-6-(5-piper

Derivatives of pyrimidine for treating acute cerebrovascular disorders

A pharmaceutical composition comprising a compound of the following general formula ?I! or its salt. STR1 wherein R1 represents aryl or a heteroaromatic group. R2 represents hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkylalkyl, hydroxyalkyl, haloalkyl, alkoxy, alkylthio, amino, monoalkylamino, dialkylamino, or phenyl. R3 and R4 independently represent hydrogen or alkyl or R3 and R4 taken together with the adjacent N atom represent a 5- through 7-membered cyclic amino group. A represents C2-10 alkylene. W represents O, S, or (CH)n (where CH may be substituted by alkyl; n is an integer of 1 or 2). X, Y, and Z may be the same or different and each represents CH (which may be substituted by alkyl), or N. Provided, however, that the case in which X, Y, and Z concurrently represent CH is excluded. The compound of the invention has excellent neuronal death inhibitory activity and is useful as a therapeutic drug for cerebrovascular diseases.