- NOVEL PROCESS FOR PREPARING NOVEL THIOXO THIENOPYRIMIDINONE DERIVATIVES AND INTERMEDIATES USED THEREIN
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The present invention relates to a preparation method of 2-thioxo thienopyrimidin-4-one represented by chemical formula 1, and an intermediate product used thereto. The preparation method of the present invention comprises the steps of: having a reaction
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Paragraph 0049; 0050
(2017/03/17)
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- Compounds
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Pyrimidone compounds of formula (I): are inhibitors of the enzyme Lp-PLA2 and are of use in treating atherosclerosis.
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Page/Page column 28
(2016/05/11)
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- Synthesis of new 1-phenylthieno[1,2,4]triazolo[4,3-a]pyrimidin-5(4H)-one derivatives
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A series of novel 1-phenylthieno[1,2,4]triazolo[4,3-a]pyrimidin-5(4H)-one derivatives 5 and 6 were synthesized by oxidative cyclization of thienopyrimidinonyl hydrazones using iodobenzene diacetate.
- Song, Yang-Heon,Son, Hoon Young
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experimental part
p. 597 - 603
(2011/07/07)
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- PIPERIDINE DERIVATIVES HAVING CCR3 ANTAGONISM
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The invention provides low molecular compounds having activity which inhibits binding of CCR3 ligands to CCR3 on target cells, i.e. CCR3 antagonists. The invention also provides compounds represented by formula (I) below, pharmaceutically acceptable acid adducts thereof, or pharmaceutically acceptable C1-C6 alkyl adducts thereof, as well as pharmaceutical compositions comprising them as effective ingredients, which are useful for treatment or prevention of diseases associated with CCR3, such as asthma and allergic rhinitis.
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- Novel heterocycles derived from substituted aroylthioureas: Synthesis of 3,1-benzothiazin-4-ones, thieno[3,2-d][1,3]thiazin-4-ones and 1,2,4-thiadiazolo[2,3-a][3,1]benzothiazin-5-ones
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A series of heterocyclic aroylthioureas has been prepared and investigated as starting materials for ring closure reactions. The formation of several new 3,1-benzothiazin-4-ones and thieno[3,2-d][1,3]thiazin-4-ones (via cyclocondensation reactions) is rep
- Guetschow
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p. 355 - 360
(2007/10/03)
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